Publications by authors named "Boitumelo Setlhare"

A significant number of the South African population still rely on traditional medicines (TM) as their primary healthcare due to their belief in their holistic healing and immune-boosting properties. However, little to no scientific data is available on the effects of most TM products on cytokine and cellular biomarkers of the immune response. Here, we evaluated the impact of traditional medicine [Product Nkabinde (PN)] in inducing cellular and cytokine biomarkers of inflammation in peripheral blood mononuclear cells (PBMCs) from eight healthy volunteers.

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Catechol dioxygenases in microorganisms cleave catechol into --muconic acid or 2-hydroxymuconic semialdehyde via the - or -pathways, respectively. The aim of this study was to purify, characterize, and predict the template-based three-dimensional structure of catechol 1,2-dioxygenase (C12O) from indigenous strain UFB2 (UFB2). Preliminary studies showed that UFB2 could degrade 40 ppm of 2,4-dichlorophenol (2,4-DCP).

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