Evaluation of a pouching system with a concave contour for people with an outward peristomal body profile.

People with an outward peristomal body profile can experience difficulties obtaining a secure seal with a flat baseplate to the peristomal skin. Baseplates with a concave contour have been designed to provide a better fit to curved body profiles and reduce the risk of leakage. In this 4-week product evaluation, 110 individuals with an outward peristomal body profile using flat one-piece pouching systems were enrolled to evaluate the impact of a concave one-piece pouching system on wear time, unplanned changes of pouching systems and use of accessories.

Evaluating the Effect of a Novel Digital Ostomy Device on Leakage Incidents, Quality of Life, Mental Well-Being, and Patient Self-Care: An Interventional, Multicentre Clinical Trial.

Most people with a stoma worry about leakage, and a quarter experience leakage of stomal effluent outside the baseplate on a monthly basis. Leakage has additional physical and psychosocial consequences, for instance, peristomal skin complications, feeling unable to cope, and self-isolation. An interventional, single-arm, multi-centre study was undertaken in the United Kingdom to evaluate a novel digital leakage notification system for ostomy care, including a support service (=test product) for 12 weeks in patients with a recent stoma formation (≤9 months).

Body Fit With a Pouching System With Concave Contour for People With an Outward Peristomal Body Profile: Effects on Leakage, Wear Time, and Quality of Life: A Randomized Controlled Cross-Over Trial.

Purpose: The purpose of the study was to investigate the fit of a two-piece pouching system with a concave-shaped skin barrier on people with an outward peristomal body profile and its effect on leakage, wear time, and quality of life (QoL) related to using an ostomy product.

Design: Randomized, controlled, open-label, cross-over trial.

Subjects And Settings: The sample comprised 53 subjects with outward peristomal body profiles and problems with leakage of ostomy effluent from their pouching system.

The economic burden of stomas in the UK: a retrospective observational study of health records and hospital encounters.

Background: Stomas divert waste from the small intestine (ileostomy), large intestine (colostomy) or ureters (urostomy), and complications are common.

Aims: This study evaluated healthcare resource utilisation (HCRU) and costs of stomas from a UK perspective.

Methods: This was a retrospective observational study of adults with new stomas (New Stoma Group) or new/existing stomas and >6 months of follow-up (Established Stoma Group) using health records linked with hospital encounters (January 2009-December 2018).

Complications and Healthcare Costs Associated With the First Year Following Colostomy and Ileostomy Formation: A Retrospective Study.

Purpose: The purpose of this study was to evaluate clinical and economic outcomes during the first year following ostomy formation.

Design: Single-center retrospective audit.

Subjects And Setting: The sample comprised 200 patients who underwent surgery leading to ileostomy or colostomy at a large English National Health Service (NHS) Trust.

Evaluating the Performance and Perception of a Stoma Bag Full-Circle Filter in People with a Colostomy or an Ileostomy-Two Randomized Crossover Trials.

Stoma bag filter-related issues, such as ballooning (the bag filling with gas), remain highly prevalent among users. The full-circle filter was purposely designed to reduce ballooning through the inclusion of a unique, full-circle pre-filter. Two similar randomized crossover trials were conducted to compare the performance of the full-circle filter with a dual filter in adults with a colostomy (n = 20) or an ileostomy (n = 20).

Leakage of stomal effluent outside the baseplate leads to rise in product usage and health professional interactions.

Background: Leakage of stomal effluent outside the baseplate that soils clothes or bedsheets is a common problem for many people with a stoma and significantly impacts their quality of life.

Aim: To understand behavioural changes for people experiencing faecal leakage outside the baseplate regarding the usage of pouching systems, supporting products and interactions with health professionals.

Methods: Retrospective, self-reported questionnaire.

Impact of stoma leakage in everyday life: data from the Ostomy Life Study 2019.

Background: Many people with a stoma experience leakage of stomal effluent.

Aim: To investigate the impact of leakage on individuals with a stoma.

Methods: The Ostomy Life Study 2019 included a survey concerning experiences with stomal effluent leakage and the validated Ostomy Leak Impact tool.

Perception of leakage: data from the Ostomy Life Study 2019.

Background: Leakage is a common problem for people with a stoma.

Aim: To investigate how people with a stoma and stoma care nurses perceive different patterns of effluent under the baseplate.

Methods: The Ostomy Life Study 2019 included a user survey and a nurse survey covering experiences of leakage and the perception of leakage.

Activity theory and medical informatics: usability, utility, and copability.

Working with health care today also means working with IT-systems. 'Human Factors' or 'user-friendly design' has been renowned as key factors for the development of safe and successful systems in many industries, not least in the IT-business. Likewise in the computerization of health care, the concepts of 'usefulness' and 'usability' will become key issues in the daily life (and death) in health care context at hospitals, at the GP's office, and in the home of the patient.

Copability, coping, and learning as focal concepts in the evaluation of computerised diabetes disease management.

Introduction: Within diabetes care, the majority of health decisions are in the hands of the patient. Therefore, the concepts of disease management and self-care represent inescapable challenges for both patient and healthcare professionals, entailing a considerable amount of learning. Thus, a computerised diabetes disease management systems (CDDM) is to be seen not merely as tools for the medical treatment, but also as pedagogical tools to enhance patient competence.

Sustained-release Madopar HBS compared with standard Madopar in the long-term treatment of de novo parkinsonian patients.

In this Danish-Norwegian randomized double-blind parallel-group multicentre study, we compared the therapeutic response of slow-release Madopar HBS to standard Madopar in 134 de novo patients with idiopathic Parkinson's disease during a 5-year period. The drugs were dosed according to the individual need of the patients. The Webster, NUDS, UPDRS and Hoehn & Yahr scales were used for evaluation of symptoms.

Pen injected apomorphine against off phenomena in late Parkinson's disease: a double blind, placebo controlled study.

The effect, therapeutic dose range, and pharmacokinetics of apomorphine, given as subcutaneous injections by a single use pen, were evaluated in the treatment of off phenomena in 22 patients with idiopathic Parkinson's disease. At study entry a placebo controlled apomorphine test was performed, and apomorphine doses were then individually titrated (mean 3.4 (range 0.

Cardiac functioning and blood pressure of 47,XYY and 47,XXY men in a double-blind, double-matched population survey.

This paper reports the electrocardiogram measures and blood pressure of 12 men with 47,XYY, 14 men with 47,XXY, and 52 matched controls with 46,XY. The abnormal karyotypes were identified in a systematic population search for XYY and XXY men. The subjects and their matched controls were examined in a double-blind fashion.

Testicular size and shape of 47,XYY and 47,XXY men in a double-blind, double-matched population survey.

This paper reports the testicular size and shape of 12 men with 47,XYY, 14 men with 47,XXY, and 52 matched controls with 46,XY. The abnormal karyotypes were identified in a systematic population search for XYY and XXY men. The subjects and their matched controls were examined in a double-blind fashion.

Torticollis caused by an infratentorial tumour: three cases.

Three cases with torticollis caused by an infratentorial tumour are presented. A father and his son both had a Lindau tumour, and another patient had an ependymoma. It is stressed that torticollis may be the predominant or only sign of an infratentorial tumour, and that torticollis should always be suspected to have an organic origin.

Clonidine in the prophylaxis of migraine.

The prophylactic effect of clonidine in a dosage of 0.05 mg twice daily was investigated in 49 patients using a double-blind, crossover trial carried out in four Departments of Neurology. Seventy-one patients were originally included but 22 patients withdrew, two of them due to side effects,the remainder because of inability to keep the requisite diary, lack of drug compliance or refusal to attend the checkups.

Tremor in XYY and XXY men.

In a double-blind, double-matched population survey, the tremor of 12 XYY, 14 XXY, and 52 XY men were studied clinically and by a special tremor recording equipment. XYY men were found to have a more pronounced tremor than XY normals, while XXY men were not found to differ in any definite way from normal XY men.