Background: The increasing frequency of induction of labor (IOL) prompts explorations into women's experiences. To inform individualized obstetric care, this study aimed to investigate the experiences of Danish pregnant women who underwent out-patient medical IOL and were not in active labor 48 h after IOL initiation.
Methods: A qualitative interview study with 28 women who had experienced prolonged IOL (all indications).
Artificial intelligence (AI) with its diverse domains such as expert systems and machine learning already has multiple potential applications in medicine. Based on the latest developments in the multifaceted field of AI, it will play a pivotal role in medicine, with a high transformative potential in multiple areas, including drug development, diagnostics, patient care and monitoring. In the pharmaceutical industry AI is also rapidly gaining a crucial role.
View Article and Find Full Text PDFCochrane Database Syst Rev
November 2024
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of discontinuing intravenous oxytocin stimulation in pregnant women during the active phase of induced or augmented labour.
View Article and Find Full Text PDFBackground: Patients who experienced postoperative delirium (POD) are at higher risk of poor outcomes like dementia or death. Previous machine learning models predicting POD mostly relied on time-aggregated features. We aimed to assess the potential of temporal patterns in clinical parameters during surgeries to predict POD.
View Article and Find Full Text PDFIntroduction: Timing of induction of labor (IOL) at term has been investigated in multiple settings. In Denmark, the 'When to INDuce for OverWeight' (WINDOW) study compares IOL at 39 weeks of gestation vs expectant management in low-risk women with obesity. However, knowledge on women's expectations of and experience with IOL is sparse.
View Article and Find Full Text PDFPostoperative delirium (POD) contributes to severe outcomes such as death or development of dementia. Thus, it is desirable to identify vulnerable patients in advance during the perioperative phase. Previous studies mainly investigated risk factors for delirium during hospitalization and further used a linear logistic regression (LR) approach with time-invariant data.
View Article and Find Full Text PDFBackground: Current guidelines regarding oxytocin stimulation are not tailored to individuals as they are based on randomised controlled trials. The objective of the study was to develop an artificial intelligence (AI) model for individual prediction of the risk of caesarean delivery (CD) in women with a cervical dilatation of 6 cm after oxytocin stimulation for induced labour. The model included not only variables known when labour induction was initiated but also variables describing the course of the labour induction.
View Article and Find Full Text PDFActa Obstet Gynecol Scand
September 2023
Introduction: Therapeutic rest refers to the usage of medication to relieve pain in women in the latent phase of labor. Very few data are available to evaluate the safety and effect of its use. The objectives of this study were to compare perinatal and labor outcomes in women who were seeking hospital care during the latent phase of labor and who were treated either with or without therapeutic rest.
View Article and Find Full Text PDFAnaesth Crit Care Pain Med
October 2023
Background: Corona Virus Disease 2019 (COVID-19) patients display risk factors for intensive care unit acquired weakness (ICUAW). The pandemic increased existing barriers to mobilisation. This study aimed to compare mobilisation practices in COVID-19 and non-COVID-19 patients.
View Article and Find Full Text PDFBackground: Guidelines advocate the use of extracorporeal cardio-pulmonary resuscitation with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in selected patients with cardiac arrest. Effects of concomitant left-ventricular (LV) unloading with Impella® (ECMELLA) remain unclear. This is the first study to investigate whether treatment with ECMELLA was associated with improved outcomes in patients with refractory cardiac arrest caused by acute myocardial infarction (AMI).
View Article and Find Full Text PDFObjective: This study aimed to review the literature comparing full-term induction of labor with expectant management in women with obesity on the risk of cesarean delivery and other adverse outcomes.
Data Sources: A literature search was performed on PubMed, EMBASE, Scopus, ClinicalTrials.gov, and the Cochrane Library.
Objective: To examine the factors associated with unexpectedly high rates of conversion to open label oxytocin in the CONDISOX trial of continuation versus discontinuation of oxytocin infusion during induced labour.
Design: Secondary retrospective analysis of data from a prospective randomised controlled trial.
Setting: Nine hospitals in Denmark and one in the Netherlands between 8 April 2016 and 30 June 2020.
(1) Background: Acute respiratory distress syndrome (ARDS) is a rare complication in multiply injured patients. Due to the rarity of ARDS development after trauma, little is known about outcomes of patients with trauma-associated ARDS compared to patients with non-trauma-associated ARDS. (2) Methods: This retrospective analysis included = 1038 ARDS patients admitted to the ARDS center of Charité-Universitätsmedizin Berlin between 2007 and 2018.
View Article and Find Full Text PDFBackground: Anticoagulation therapy with heparin is a frequent treatment in intensive care units and is monitored by activated partial thromboplastin clotting time (aPTT). It has been demonstrated that reaching an established anticoagulation target within 24 hours is associated with favorable outcomes. However, patients respond to heparin differently and reaching the anticoagulation target can be challenging.
View Article and Find Full Text PDFRoutinely collected electronic health records (EHR) in clinical information systems (CIS) are often heterogeneous, have inconsistent data formats and lack of documentation. We use the well-known open-source database schema of MIMIC-IV to address this issue aiming to support collaborative secondary analysis. Over 154 million data records from a German ICU have already been mapped and inserted into the schema successfully.
View Article and Find Full Text PDFIntroduction: Worldwide, the estimated prevalence of urinary incontinence is 8.7%. Urinary incontinence is more frequent in women than in men.
View Article and Find Full Text PDFIntroduction: Little is known about the optimal simulation-based team training in obstetric emergencies. We aimed to review how simulation-based team training affects patient outcomes in obstetric emergencies.
Material And Methods: Search Strategy: MEDLINE, Embase, Cochrane Library, and Cochrane Central Register of Controlled Trials were searched up to and including May 15, 2021.
Objective: To determine whether discontinuing oxytocin stimulation in the active phase of induced labour is associated with lower caesarean section rates.
Design: International multicentre, double blind, randomised controlled trial.
Setting: Nine hospitals in Denmark and one in the Netherlands between 8 April 2016 and 30 June 2020.
Am J Obstet Gynecol MFM
May 2020
Background: Acute fatty liver of pregnancy is a rare but serious complication in the last trimester of pregnancy or postpartum period. Data on the recurrence risk are largely unavailable, as only case reports or very small case series exist in which only 1 woman had recurrent acute fatty liver of pregnancy.
Objective: We aimed to estimate the risk of acute fatty liver of pregnancy recurrence and to compare disease severity and gestational age between primary and recurrent disease using patient-provided data from an acute fatty liver of pregnancy social media patient group.
Introduction: It is common practice after a pelvic exam to ask a woman to put her pants on, before she is given verbal information. We aimed to compare short-term memory in undressed versus dressed women.
Methods: Thirty-six female Ob/Gyn doctors were randomised to receive verbal information while undressed and still in a lithotomy position, or once dressed again.
Background: When determining optimal treatment regimens, patient reported outcomes including satisfaction are increasingly appreciated. It is well established that the birth experience may affect the postnatal attachment to the newborn and the management of subsequent pregnancies and deliveries. As we have no robust validated Danish tool to evaluate the childbirth experience exists, we aimed to perform a transcultural adaptation of the Childbirth Experience Questionnaire (CEQ) to a Danish context.
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