Concept formation vs. logistic regression: predicting death in trauma patients.

This study compares two classification models used to predict survival of injured patients entering the emergency department. Concept formation is a machine learning technique that summarizes known examples cases in the form of a tree. After the tree is constructed, it can then be used to predict the classification of new cases.

Extracting knowledge from large medical databases: an automated approach.

Tools which can uncover patterns in patients' records and then make predictions based on that knowledge are and will continue to be high priority in many medical informatics groups. These tools are impacting the performance of outcome studies by discovering patterns which can then be verified with standard statistical tools. This paper demonstrates INC2.

Information, intelligence, and interface: the pillars of a successful medical information system.

This paper addresses three key issues facing developers of clinical and/or research medical information systems. 1. INFORMATION.

Concept formation vs. logistic regression: predicting death in trauma patients.

This paper discusses two classification models, one based on concept formation and the other using standard logistic regression. The models are first explained in some detail and then evaluated on the same population of trauma patients. The goal of both systems is to predict the outcome of those patients.

Turning medical data into decision-support knowledge.

Advances in information collection and analysis are reaching the point of providing physicians with the help of computer-based assistants. These systems will provide rapid second opinions to physicians in a clinical setting as well as assist them in the analysis of large sets of patient descriptions for research purposes. This paper presents INC2.

Logistic growth curve of chickens: heritability of parameters.

Parameters of the logistic function of growth, fit to individual body weight curves of two randombred control populations of each sex of chickens from hatching to 45 weeks of age, were evaluated. Growth-rate constant and age at the infection point in the curve were estimated by the method of sample quantiles from individual weekly body weights of 225 males and 281 females of the Rhode Island Red (RIR) line, and 164 males and 239 females of the White Leghorn (WL) line. Heritability estimates, based on correlation among full-sibs, of growth rate constant were 0.

Logistic growth curve of chickens: a comparison of techniques to estimate parameters.

Parameters of a mathematical function of growth, fit to the body weight curve of two randombred control populations of each sex of chickens from hatching through 45 weeks of age, were estimated. The logistic function was chosen from among growth formulae that express rate of gain as a function of weight at a given time and gain to be made. Two logistic parameters, growth-rate constant and age at the point of inflection, were estimated by the methods of sample quantiles and nonlinear regression from weekly mean body weights of 225 males and 281 females of the Rhode Island Red (RIR) line, and 164 males and 239 females of the White Leghorn (WL) line.

Estimation of the interaction of dams with hatches, sires in breed, and breed of sire for five traits in the fowl.

An experiment was designed to estimate the interaction of dams by hatches, dams by sires in the same breed, and dams by breed of sires. White Leghorn dams were mated sequentially to two White Leghorn sires and two New Hampshire sires, and two hatches were measured for each sire. Two replicates were included, each with different sires and dams.

Effect of thiouracil on response to heat stress of White Leghorn lines selected for fast and slow gain in two temperatures.

Four lines of White Leghorns previously selected for fast and slow gain from 5 to 9 weeks of age in a hot (32.2 C) and in a cold (21.1 C) selection environment were grown from 5 to 9 weeks in the same two temperature environments.

Performance at two rearing temperatures of White Leghorn lines selected for increased and decreased survival under heat stress.

Body weight and percent mortality resulting from heat stress at 40.6 C were determined on two lines selected for resistance and susceptibility to heat stress by the Florida Agricultural Experiment Station and reared from 5 to 9 weeks of age in two temperatures, 32.2 C and 21.

Survival under heat stress of lines selected for fast and slow growth at two temperatures.

Two replicates of four lines of White Leghorn chickens previously selected for fast and slow gain from 5 to 9 weeks of age in a hot (32.2 C) and cold (21.1 C) selection environment were grown from 5 to 9 weeks in the hot and cold temperature environments and then subjected to high temperature stress at 40.

Response to selection at two temperatures for fast and slow growth from five to nine weeks of age in poultry.

Cornell Control White Leghorn chicks were grown in a common environment to five weeks of age and selected for fast and slow gain in body weight from five to nine weeks of age at two temperatures, 21.1 degrees (cold) and 32.2 degrees (hot), during which time a constant 50% relative humidity was maintained.

An experimental test of the efficiency of family selection in chickens.

Responses to single trait selection on individual phenotype and sire-family mean phenotype for survivor's egg weight and rate of lay were measured for a single generation in 13 replicates. Each replicate-selection criterion-trait subclass consisted of eight sire families or 72 females measured and was reproduced from the best 25% of the families or individuals. The realized heritability of egg weight was 0.

A replicated single generation test of a restricted selections index in poultry.

Predicted and realized responses in a single generation of mass selection for an index and for its component traits were compared. The index included the log transformed traits determining egg mass in chickens to 40 weeks of age (days tested from sexual maturity, egg weight, rate of lay). The index was restricted to allow no increase in log days tested.

Light effects during incubation on lines of White Leghorns selected for fast and slow hatching.

Eggs from White Leghorn lines selected for fat and slow hatching time were incubated in continuous light and in unlighted incubators. The fast hatching line averaged 48 hours shorter in incubation time than the slow hatching line. The light treated eggs averaged five hours earlier in hatching time than the unlighted treatment.

Designing artificial selection experiments for specific objectives.

The observed genetic gain (DeltaP) from selection in a finite population is the possible expected genetic gain E(Delta G) minus the difference in inbreeding depression effects in the selected and control lines. The inbreeding depression can be avoided by crossing the control and selected male symbol and female symbol parents to unrelated mates and summing the observed gains. The possible expected gain will be reduced by an amount D from the predicted gain because of the effects of the genetic limit and random genetic drift, the magnitude of which is a function of effective population size, N.

Genetic gains from reciprocal recurrent and within-line selection for egg production in the fowl.

Selection for survivors percent egg production from first egg to 40 weeks of age was conducted for six generations. Within-line selection (WLS) on the basis of an index of individual records plus sire family and dam family means was compared with reciprocal recurrent selection (RRS) based on sire family selection among cross progeny. Genetically heterogeneous synthetic populations, the Cornell Control and the Purdue Pool strains were used.