QUANTITATIVE MORPHOLOGICAL ASPECTS OF THE STUDY OF THE FEATURES OF THE REMODELING OF THE HEMOMICROCIRCULATORY CHANNEL OF THE TESTICLES UNDER THE ACTION OF ALUMINUM CHLORIDE ON THE BODY.

Objective: The aim: To conduct a morphometric analysis of the features of the remodeling of vessels of the hemomicrocirculatory channel of the testicles under the action of aluminum chloride on the body.

Patients And Methods: Materials and methods: The testicles of 52 white male Wistar rats were morphologically studied, which were divided into two groups: intact and animals injected with aluminum chloride at a dose of 100 mg/kg.

Results: Results: The long-term effect of aluminum chloride on the body led to pronounced changes in the quantitative morphological indicators of the vessels of the hemomicrocirculatory channel of the testes compared to the control ones.

The effect of gel "Xeliogel" at the stages of the regeneration of aseptic burn wound in the experiment.

Unlabelled: Due to the problem of treating some types of burns, it is necessary to develop new drugs. For this purpose, pharmacological studies of developed gel "Xeliogel" (based on biological material with regenerating action), which accelerates the healing of superficial burns, have been developed and previously carried out.

Aim: The aim of this work was to establish the histological changes of the burn wound in the dynamics and after the experimental thermal injury and in the conditions of application of the gel "Xeliogel".

Analysis of patients' rehabilitation results after surgical treatment of diabetes complications.

Unlabelled: The results of treatment of patients with diabetic foot syndrome (DFS) remain unsatisfactory, 34% of patients have another wound defect in the foot within 1 year, and the recurrence rate within 5 years is 70%.

Aim: The aim of the study was to determine the indicators of physical capabilities and self-care of patients after organ-sparing surgery due to DFS.

Materials And Methods: 6-12 months after discharge from the surgical hospital, all patients were sent questionnaires of the functional scale of the lower extremities.

Substantiation of attention around antioxidants of plant origin for use in complex pharmacotherapy of diseases of the oral cavity.

As is known, phytochemical substances can play an important role in maintaining homeostasis and the prevention of chronic diseases, including diseases of the mouth. The most popular are polyphenols, which are very common in fruits, vegetables, beverages, cereals. There are data on their polyvalent pharmacological activity: antioxidant, antiinflammatory, detoxifying properties, antihypoxic, immunocorrective action, the ability to improve the endothelial function, etc.

Analysis of the results of patients treatment with metabolic syndrome, diabetic foot syndrome combined with diastolic dysfunction of the left ventricle.

Unlabelled: Obesity is one of the most serious and common risk factors for cardiovascular disease that increases the risk of type 2 diabetes.

Aim: The aim of the study was to analyze the features of disorders of diastolic function of the left ventricle and the oxygenation of arterial and venous blood in patients with diabetic foot syndrome and metabolic syndrome with diastolic dysfunction of the left ventricle in its complex treatment with the using a course of hyperbaric oxygen therapy.

Materials And Methods: An examination of 32 patients with diabetic foot syndrome, neuro-ischemic form (I stage - 8 patients, II stage - 24 patients) and metabolic syndrome, to determine an assessment was made of diastolic function of the left ventricle, determination of saturation of arterial and venous blood, oxygen content in arterial and venous blood, arterio-venous difference in oxygen.

Characteristics of structured medical hemostatic sponges as a medical devices for stop bleeding and for close the wound.

Unlabelled: Medical sponge is a tool that has absorbent and antiseptic properties, as well as stimulates tissue regeneration and is used in surgery, neurosurgery, dentistry, otolaryngology and gynecology to stop blood loss or to close wound surfaces (burns, trophic ulcers). To summarize the information of the professional literature on medical (hemostatic) sponges, their classification and applications, the areas of their use in medical practice and also modern excipients and active pharmaceutical ingredients that can be used in their technology.

Aim: The aim of the study was to summarize data on the characteristics, classification of medical sponges, auxiliary substances and active pharmaceutical ingredients used in the technology of these agents and medical use.

Therapeutic efficacy of the developed gel "Xeliogel" on a burn wound model in rats.

Unlabelled: Among the high-tech methods of wound therapy, the leading place belongs to the technology of manufacture and use of cryolyophilized tissues and bioorganic drugs. Crushed xenoderm's powder stimulates the regenerative processes of the skin and improves the healing process of wounds, as it is enriched with macro- and microelements, amino acids and other cellular elements necessary for skin regeneration.

Aim: The aim of this work was to study the wound-healing effectiveness of the developed gel "Xeliogel" on the animal model of aseptic superficial burns.