[Membranotropic effect of some triterpene glycosides possessing immunostimulating properties].

The peculiarities of the interaction between cell membrane lipids and triterpene glycosides from holothurians Apostichopus japonicus S. and Cucumaria japonica (holotoxin A1 and cucumarioside A2-2, respectively) were studied in comparison with plant saponins from Quillaja saponaria, known as hemolytic, adjuvant, and structure-forming components of immunostimulating complexes. Similar to Quillaja saponins, the sea glycosides, holotoxin A1 and cucumarioside A2-2 were shown to possess a high hemolytic activity (2.

[The forensic medical significance of brain tumors].

Thirty-three cases of death because of brain tumors are described. The age and sex of dead subjects are analyzed, as are the place and causes of death and morphologic features of the tumors. Neuroectodermal tumors of the glioblastoma or neurinoma types were the most incident.

[The prognosis of small-cell cancer and malignant carcinoid of the lung].

The morphological examination of 228 small-cell carcinomas and carcinoids of the lung, and evaluation of carcinoid tumor cataplasia versus posttreatment survival identified well-, moderately and poorly differentiated carcinoids. Well- and moderately differentiated tumors have a favorable clinical course and prognosis, though they tend to metastasize. Poorly differentiated carcinoids are characterized by an unfavorable course which is virtually similar to that of small-cell cancer.

[Isolation of the proteolytic complex from industrial waste waters from streptomycin production].

Dynamics of industrial biosynthesis of polyenzymic Streptomyces griseus system proteases and changes in their activities are studied in the process of streptomycin production. The method to isolate protease preparations is developed with optimization of production cycles of the stabilization, vacuum-concentration, ballast protein salting-out and lyophilization stages. The preparation is low toxic, retains 98% of the proteolytic activity at the temperature of 60 degrees C, 30 and 80%--under the effect of EDTA and urea, the activity maximum is at pH 7.