[Immunogenicity of attenuated reassortants of influenza A virus /Leningrad/134/47/57 (H2N2) for mice, depending on their genome].

Reassortants of cold-adapted strain A/Leningrad/134/47/57 (H2N2) and virulent strain A/PR/8/34 (H1N1), modeling genomic composition of vaccinal strains, were tried in mouse experiments. Reassortants' genomes included the major part (5, 6, or 7) from cold-adapted strain and 1 to 3 genes of virulent strain. All the tested reassortants did not differ by temperature sensitivity or cold adaptation phenotypes, did not cause the death of mice, but differed by the level of reproduction in murine lungs and by immunogenicity.

[Contribution of A. N. Filatov in the solution of problems concerning the preparation of therapeutic blood and blood substitutes].

A review of achievements of academician A. N. Filatov in the field of creation of preparations of blood and blood substitutes is presented.

[Oxygen transport in rats following total blood replacement with solutions of high-molecular modified hemoglobin].

In acute experiments on Wistar rats, after replacement of 92-94% of the blood with solution of high-molecular modified hemoglobin (HMH), 10.1-11.2 g%, the latter's oxygen transport function was studied.

[Use of gelvisol in the early postoperative period in patients with diseases of the abdominal organs].

The substance gelvisol obtained in Leningrad Research Institute of Hematology and Blood Transfusion was employed in 198 patients with abdominal organs pathology. There was noted a positive effect of the peroral plasma substitutor on the circulatory blood volume and its components, electrolytic balance, general condition of the operated patients. The authors have elaborated the method of gelvisol administration both per os (30-50 ml each 1-2 hours; up to 1000-2000 ml a day) and in intraintestinal administration via a sound.