Pathogenesis of the vitreous cloud emanating from subretinal hemorrhage.

Objective: To determine the cellular mechanism that allows subretinal hemorrhage to cloud the vitreous.

Methods: We simulated subretinal hemorrhage in a rabbit model by injecting autologous blood beneath the retina. At the first appearance of a cloud in the vitreous a vitrectomy was performed and using a surgical microscope, the retina was searched for breaks.