Infliximab dependency is related to decreased surgical rates in adult Crohn's disease patients.

Background: Infliximab dependency in children with Crohn's disease (CD) has recently been described and found to be associated with a decreased surgery rate.

Aim: To assess infliximab dependency of adult CD patients, evaluate the impact on surgery, and search for possible clinical and genetic predictors.

Methods: Two hundred and forty-five CD patients treated with infliximab were included from Danish and Czech Crohn Colitis Database (1999-2006).

[Diagnosing lactose intolerance in adults].

Introduction: Primary lactose malabsorption, adult type, is associated with the genotype CC in a lactase gene regulatory sequence (LCT-13910). In contrast, the genotype CT or TT in this position correlates with normal lactose absorption. Genotyping was implemented for routine testing of patients for primary lactose intolerance.