Background: Acute illness states with increased metabolic demand can precipitate severe thiamine deficiency if physiologic needs exceed endogenous stores and supplementation. Patients with preexisting risk factors such as parenteral nutrition (PN) dependence, eating disorders, gastrointestinal disorders, or surgeries are especially vulnerable.
Case Summary: A 9-year-old girl with short bowel syndrome receiving long-term PN, including standard thiamine supplementation, presented with refractory shock following aspiration.
Background: Population screening for risk of type 1 diabetes (T1D) has been proposed to identify those with islet autoimmunity (presence of islet autoantibodies). As islet autoantibodies can be transient, screening with a genetic risk score has been proposed as an entry into autoantibody testing.
Methods: Children were recruited from eight general pediatric and specialty clinics across Virginia with diverse community settings.
Exp Astron (Dordr)
October 2023
In an ideal germanium detector, fully-absorbed monoenergetic -rays will appear in the measured spectrum as a narrow peak, broadened into a Gaussian of width determined only by the statistical properties of charge cloud generation and the electronic noise of the readout electronics. Multielectrode detectors complicate this picture. Broadening of the charge clouds as they drift through the detector will lead to charge sharing between neighboring electrodes and, inevitably, low-energy tails on the photopeak spectra.
View Article and Find Full Text PDFArtificial intelligence (AI) is a division of computer science that allows machines to emulate human cognitive processes. In dentistry, AI is applied in clinical decision-making and can aid in detecting disease and predicting patterns based on existing data sets. AI can assist clinicians by quickly analyzing massive amounts of data to improve workflow, identify patterns of disease, provide risk assessment, and create individualized patient-centered treatment plans.
View Article and Find Full Text PDFA primary focus of research on conspiracy theories has been understanding the psychological characteristics that predict people's level of conspiracist ideation. However, the dynamics of conspiracist ideation-i.e.
View Article and Find Full Text PDFObjectives: To describe the characteristics, critical care resource requirements, and outcomes of children who were hospitalized after a Pediatric Intensive Care Unit (PICU) consult in the Emergency Department (ED).
Methods: In this single-centre retrospective cohort study, we conducted chart reviews for children (<18 years) hospitalized following a PICU consult in the ED to examine patient characteristics, timing of consult, ED length of stay, Medical Emergency Team (MET) utilization, PICU nursing workload, and critical care interventions for children who were and were not admitted to the PICU.
Results: During the one-year study period, 247 PICU consults were performed in the ED resulting in 161 (65.
Recent work has found that an individual's beliefs and personal characteristics can impact perceptions of and responses to the COVID-19 pandemic. Certain individuals-such as those who are politically conservative or who endorse conspiracy theories-are less likely to engage in preventative behaviors like social distancing. The current research aims to address whether these individual differences not only affect people's reactions to the pandemic, but also their actual likelihood of contracting COVID-19.
View Article and Find Full Text PDFThe COVID-19 disease pandemic is one of the most pressing global health issues of our time. Nevertheless, responses to the pandemic exhibit a stark ideological divide, with political conservatives (versus liberals/progressives) expressing less concern about the virus and less behavioral compliance with efforts to combat it. Drawing from decades of research on the psychological underpinnings of ideology, in four studies (total = 4441) we examine the factors that contribute to the ideological gap in pandemic response-across domains including personality (e.
View Article and Find Full Text PDFCurr Opin Anaesthesiol
August 2021
Purpose Of Review: Nonoperating room anesthesia (NORA) procedures continue to increase in type and complexity as procedural medicine makes technical advances. Patients presenting for NORA procedures are also older and sicker than ever. Commensurate with the requirements of procedural medicine, anesthetic monitoring must meet the American Society of Anesthesiologists standards for basic monitoring.
View Article and Find Full Text PDFA study involving over 2000 online participants (US residents) tested a general framework regarding compliance with a directive in the context of the COVID-19 pandemic. The study featured not only a self-report measure of social distancing but also virtual behavior measures-simulations that presented participants with graphical depictions mirroring multiple real-world scenarios and asked them to position themselves in relation to others in the scene. The conceptual framework highlights three essential components of a directive: (1) the source, some entity is advocating for a behavioral change; (2) the surrounding context, the directive is in response to some challenge; and (3) the target, the persons to whom the directive is addressed.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2021
Past research has established the value of social distancing as a means of deterring the spread of COVID-19 largely by examining aggregate level data. Locales in which efforts were undertaken to encourage distancing experienced reductions in their rate of transmission. However, these aggregate results tell us little about the effectiveness of social distancing at the level of the individual, which is the question addressed by the current research.
View Article and Find Full Text PDFJ Cosmol Astropart Phys
August 2020
The precise measurement of cosmic-ray antinuclei serves as an important means for identifying the nature of dark matter and other new astrophysical phenomena, and could be used with other cosmic-ray species to understand cosmic-ray production and propagation in the Galaxy. For instance, low-energy antideuterons would provide a "smoking gun" signature of dark matter annihilation or decay, essentially free of astrophysical background. Studies in recent years have emphasized that models for cosmic-ray antideuterons must be considered together with the abundant cosmic antiprotons and any potential observation of antihelium.
View Article and Find Full Text PDFInadequate supply of filtering facepiece respirators (FFRs) for healthcare workers during a pandemic such as the novel coronavirus outbreak (SARS-CoV-2) is a serious public health issue. The aim of this study was to synthesize existing data on the effectiveness of ultraviolet germicidal irradiation (UVGI) for N95 FFR decontamination. A systematic review (PROSPERO CRD42020176156) was conducted on UVGI in N95 FFRs using Embase, Medline, Global Health, Google Scholar, WHO feed, and MedRxiv.
View Article and Find Full Text PDFAfter the generally unexpected outcome of the 2016 U.S. presidential election, many explanations were proposed to account for the results.
View Article and Find Full Text PDFIn this investigation, the utility of a static light scattering (SLS) technique to characterize aggregate morphology of two-dimensional engineered nanomaterials (2D ENMs) was systematically evaluated. The aggregation of graphene oxide (GO) and lithiated-molybdenum disulfide (Li-MoS) were measured and compared to that of a spherical reference colloid, carboxylate-modified latex (CML) nanoparticles. The critical coagulation concentration (CCC) for all dispersions was determined via analysis of aggregation kinetics using time-resolved dynamic light scattering.
View Article and Find Full Text PDFThe intersection of SES and race-ethnicity impact youth development at the family and neighborhood levels. The confluence of neighborhood structural and social characteristics intersects to impact parenting multiple ways. Within lower-income neighborhoods, there is variability in economic and racial-ethnic demographics and social characteristics and a multitude of different lived experiences.
View Article and Find Full Text PDFCurr Opin Anaesthesiol
August 2019
Purpose Of Review: Nonoperating room anesthesia (NORA) is the fastest growing segment of anesthetic practice. This review provides an overview of knowledge and trends that will need to be introduced to residents as part of their education.
Recent Findings: Topics for the future include, but are not limited to, new medications, artificial intelligence and big data, monitoring depth of hypnosis, translational innovation and collaboration, demographic changes, financial driving forces, destination hubs, medical tourism, and new approaches to education training and self-management.