[Reconstructive procedures in women with irradiation injuries of urinary tract: change of a paradigm].

Introduction: Radiation therapy is one of the main methods of treating pelvic malignant tumors, which provides good oncological results. Specific features of the pelvic anatomy may result in various radiation injuries of adjacent organs, which are complicated by genitourinary fistulas, post-radiation fibrosis with the formation of hydronephrosis, microcyst, reducing the quality of life.

Aim: To describe the relevance and importance of the correct choice of surgical treatment in patients with post-radiation urinary tract injuries.

[Tracheobronchial stenting in patients with non-resectable tumors complicated by airway stenosis].

Objective: To study the results and efficiency of tracheobronchial stenting in patients with unresectable tumors complicated by stenosis of central airways.

Material And Methods: We analyzed the results of tracheobronchial stenting in 23 patients with unresectable tumors complicated by stenosis of central airways between 2016 and 2021.

Results: Technical and clinical success rate was 100%.

Increment of the incidence of glioblastoma following decrease in the incidence of brain tumors in 2000-2020: a population-based registry study.

Background: Prevalence and dynamics of certain morphological variants of neuroglial brain malignancies (ICD-10 C71) are unknown in the Russian Federation.

Objective: To assess the incidence of neuroglial brain malignancies in 2000-2020 considering individual records of morphologically verified cases in the cancer registry of the Arkhangelsk region.

Material And Methods: We analyzed overall and age-adjusted incidence of neuroglial brain malignancies in 2000-2020 considering morphological subtypes of tumor.

Contextualizing the scope, scale, and speed of energy pathways toward sustainable development in Africa.

Faced with interrelated challenges of climate change and energy crises, Africa's future energy system orientation could be steered toward sustainable development. In this study, we contextualized diverging fossil fuels-dominated and renewable energy-based pathways toward sustainable development in Africa. A novel and sophisticated techno-economic energy modeling tool is used to describe the scope of the pathways in high geo-spatial and full hourly resolution for Africa covering the entire energy system.

The role of renewables for rapid transitioning of the power sector across states in India.

Recent events like heatwaves and abnormal rainfall are a glimpse of the devastating effects of human induced climate change. No country is immune to its effects, but a developing country like India is particularly vulnerable. This research, for the individual states of India, explores the technical feasibility and economic viability of a renewable transition pathway for the power sector.

[A place of silodosin in the treatment of LUTS/BPH according to evidence-based medicine and real clinical practice].

Lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) are common disorder in older men. The mainstay of conservative treatment for BPH is 1-adrenoblockers. A review of the literature on silodosin, a selective -adrenergic blocker, is discussed in the article.

Toward a Common Performance and Effectiveness Terminology for Digital Proximity Tracing Applications.

Digital proximity tracing (DPT) for Sars-CoV-2 pandemic mitigation is a complex intervention with the primary goal to notify app users about possible risk exposures to infected persons. DPT not only relies on the technical functioning of the proximity tracing application and its backend server, but also on seamless integration of health system processes such as laboratory testing, communication of results (and their validation), generation of notification codes, manual contact tracing, and management of app-notified users. Policymakers and DPT operators need to know whether their system works as expected in terms of speed or yield (performance) and whether DPT is making an effective contribution to pandemic mitigation (also in comparison to and beyond established mitigation measures, particularly manual contact tracing).

[Technical features of esophageal stent deployment].

Objective: To work out the optimal technique of endoscopic stenting of the esophagus (ESE) using various delivery devices (DD); to analyze immediate and long-term results of stenting depending on the type of DD.

Material And Methods: ESE results were studied in 83 patients. Group 1 included 41 patients with implantation of metal stents delivered on a knitted tubular casing (21 stents with proximal opening and 20 stents with distal opening).

European smelt Osmerus eperlanus in the eastern Gulf of Finland, Baltic Sea: Stock status and fishery.

In the eastern Gulf of Finland, European smelt Osmerus eperlanus occurs as an anadromous ecological form that spawns in coastal, low-salinity zones and in several rivers entering the gulf, most importantly in the River Neva. Osmerus eperlanus is a key commercial fish species for the population of St. Petersburg, and the city's fish symbol.

Radical transformation pathway towards sustainable electricity via evolutionary steps.

A transition towards long-term sustainability in global energy systems based on renewable energy resources can mitigate several growing threats to human society simultaneously: greenhouse gas emissions, human-induced climate deviations, and the exceeding of critical planetary boundaries. However, the optimal structure of future systems and potential transition pathways are still open questions. This research describes a global, 100% renewable electricity system, which can be achieved by 2050, and the steps required to enable a realistic transition that prevents societal disruption.

[Are large adrenal neoplasms technical limitation for laparoscopic adrenalectomy?].

Aim: To study surgical features of laparoscopic adrenalectomy in patients with large adrenal neoplasms.

Material And Methods: The results of 32 laparoscopic adrenalectomy procedures were analyzed in patients with adrenal neoplasms over 5 cm. The control group consisted of 67 patients with adrenal neoplasms up to 5 cm.

Implementation and Evaluation of an Algorithm for Cryptographically Private Principal Component Analysis on Genomic Data.

We improve the quality of cryptographically privacy-preserving genome-wide association studies by correctly handling population stratification-the inherent genetic difference of patient groups, e.g., people with different ancestries.

[Pectoral-retroauricular approach for endoscopic parathyroidectomy (experimental study)].

Aim: To develop and investigate in the experiment the method of endoscopic parathyroidectomy in order to prevent intraoperative 'conflict of the instruments' and to reduce surgical trauma via extracervical approach.

Material And Methods: The results of 10 experimental endoscopic parathyroidectomies with original pectoral-retroauricular approach were analyzed.

Results: Mean time of surgery was 77.

[The minimally invasive video-assisted parathyroidectomy for primary hyperparathyroidism].

Aim: To study feasibility, effectiveness and safety of minimally invasive video-assisted parathyroidectomy in patients with primary hyperparathyroidism; to define the advantages and disadvantages of this technique compared with conventional open surgery.

Material And Methods: The study includes the results of 33 minimally invasive video-assisted parathyroidectomies performed in patients with primary hyperparathyroidism. The control group included 36 patients who underwent conventional open surgery.

Electricity system based on 100% renewable energy for India and SAARC.

The developing region of SAARC (South Asian Association for Regional Cooperation) is home to a large number of people living below the poverty line. In future, providing affordable, universally accessible, reliable, low to zero carbon electricity in this region will be the main aim. A cost optimal 100% renewable energy system is simulated for SAARC for the year 2030 on an hourly resolved basis.

Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

Power systems for South and Central America based on 100% renewable energy (RE) in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC) transmission grid development levels (region, country, area-wide) and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG).

[Long-term prospective observation of patients with hypertrophic cardiomyopathy].

This paper summarizes results of a long-term prospective study of the patients with hypertrophic cardiomyopathy (GCMP) divided into two groups, one with progressive disease (42%) the other with its stable course (58%). The progress of GCMP was not associated with thickening of the left ventricle. Predictors of the progress included manifest and extensive asymmetry of myocardial hypertrophy.

[Diastolic dysfunction in hypertrophic nonobstructive cardiomyopathy].

Objective: The purpose of research was to assess the availability and prevalence of types of diastolic dysfunction of the left ventricle (LV) in hypertrophic nonobstructive cardiomyopathy (NHCM).

Methods: 97 NHCM patients. Mean age 42.

A new way to protect privacy in large-scale genome-wide association studies.

Motivation: Increased availability of various genotyping techniques has initiated a race for finding genetic markers that can be used in diagnostics and personalized medicine. Although many genetic risk factors are known, key causes of common diseases with complex heritage patterns are still unknown. Identification of such complex traits requires a targeted study over a large collection of data.

[Spherical remodeling of left atrium in hypertrophic nonobstructive cardiomyopathy].

We examined 86 patients with various forms and variants of hypertrophic cardiomyopathy (HCM). Examination of 69 patients with nonobstructive form of the disease included echocardiography. The state of left atrium (LA) was studied by measurement of its systolic and diastolic longitudinal and transversal dimensions with calculation of main parameters of contractility.

Polyhedral cobalt(II) and iron(II) siloxanes: synthesis and x-ray crystal structure of [(RSi(OH)O2)Co(OPMe3)]4 and [(RSiO3)2(RSi(OH)O2)4(mu3-OH)2Fe8(THF)4] (R = (2,6-iPr2C6H3)N(SiMe3)).

The cobalt(II) and iron(II) siloxane compounds were prepared by the reaction of lipophilic N-bonded silanetriol 1 with metal silylamides M[N(SiMe3)2]2 (M = Co (2), Fe (3)) in a 1:1 and 3:4 molar ratio, respectively. A plot of 1/chi versus temperature in the range of 2-300 K indicates the paramagnetic behavior of 2 and 3. The composition and molecular structures of 2 and 3 were fully determined by IR, elemental analysis, and X-ray crystal structural analyses.

Superheavy hydrogen (5)H.

Experimental search for (5)H using a secondary beam of (6)He has been performed. The transfer reaction (1)H((6)He,(2)He)(5)H was studied by detecting two protons emitted from the decay of (2)He. A peak consistent with a (5)H resonance at 1.