[Acute poisoning with trichloroethylene, toluene and xylene--toxicokinetic mathematical models and clinical experiments].

The paper presents a review of toxic activity of three solvents and mathematical models of their metabolism and different routes of elimination. Special attention was paid to clinical difficulties and complications which may occur during acute poisonings, especially the immunological disorders and coagulation disturbances.

[Use of the EDP (electronic data processing) technic in the control of digitalis-glycoside therapy].

A computer programme for the digitalis therapy developed by us was tested in 282 patients with heart insufficiency. It helps to control the course of the therapy, to establish the optimum fully effective dose of the individually determined glycoside sensitivity and to decrease significantly the danger of an overdosage.