[6 months' results of coronary angioplasty after thrombolysis of myocardial infarction].

Transluminal coronary angioplasty (TCA) has become the treatment of choice of residual stenosis after thrombolysis for myocardial infarction, but the long-term results of TCA are imperfectly evaluated. Seventy patients underwent TCA after thrombolysis on account of a significant (greater than 50 p. 100) residual stenosis of the artery responsible for the infarction.

Larynx: MR imaging at 2.35 T.

To study the consequences of an improvement in spatial resolution, the authors compared magnetic resonance (MR) images of nine laryngeal specimens with whole-organ histologic slides of the same specimens. Five of the specimens were obtained during laryngectomies performed on patients with high-stage tumors of the larynx. Four specimens were from patients with no known disease.

Hunting behavior of wild chimpanzees in the Taï National Park.

Hunting is often considered one of the major behaviors that shaped early hominids' evolution, along with the shift toward a drier and more open habitat. We suggest that a precise comparison of the hunting behavior of a species closely related to man might help us understand which aspects of hunting could be affected by environmental conditions. The hunting behavior of wild chimpanzees is discussed, and new observations on a population living in the tropical rain forest of the Taï National Park, Ivory Coast, are presented.

Magnetic resonance imaging of the brain in congenital cytomegalovirus infection.

Ten children (age 2 months to 8 years) with a congenital cytomegalovirus (CMV) infection were studied by magnetic resonance imaging (MRI) using a 2.35 Tesla magnet. CMV infection was confirmed by serological investigations and virus culture in the neonatal period.

Developmental stages of human brain: an MR study.

The differentiation of the telencephalon (TC) gyri and the myelination of TC and diencephalon were analyzed quantitatively in 50 children, 32-240 weeks' postconceptional age (PCA). For this purpose, a four-stage grading system was developed by correlating magnetic resonance images from age-matched postmortem brains with subsequently prepared myelin-stained macroslices. Gyration and myelination progressed in a occipito-rostral direction.

Combined application of MR imaging and spectroscopy in neonates and children: installation and operation of a 2.35-T system in a clinical setting.

Published pediatric magnetic resonance (MR) imaging results are usually obtained with medium-field-strength whole-body systems, while MR spectroscopy is done on a different high-field-strength/small-bore laboratory system. The authors investigated metabolism and structural development of the brain in over 100 neonates and children with combined MR imaging and spectroscopy at 2.35 T.

[Magnetic resonance in pediatric research and clinical practice. II. Studies on the development and pathology of the brain in neonates, infants and young children].

We are investigating metabolism and morphological differentiation of the developing brain in neonates and children under non-invasive conditions combining MR imaging (MRI) with spectroscopy (MRS) on a high-field/small-bore (2.35 Tesla/40 cm) system. By the end of 1987, 116 neonates, infants and young children with various perinatal problems, congenital abnormalities and different neurological diseases have been examined with MRI.

[Magnetic resonance in pediatric research and clinical practice. I. What can we expect from this new method?].

Nuclear Magnetic Resonance (NMR) was first observed over 40 years ago and has recently also entered the field of human medicine. It currently attracts increasing attention from biologists and clinicians alike, and the scope of its different applications is in a phase of explosive development. Two principle developments of the MR method are taking place over the recent years and are of special interest for pediatricians and neonatologists.

[Home thrombolysis for myocardial infarction. A multicenter study of the feasibility and evaluation of short-term prognosis].

It has been proven since 1986 that in myocardial infarction the sooner thrombolysis is performed the better. Forty-four patients were selected to enter a double-blind randomized trial in which they received either an acylated plasminogen streptokinase activator complex or a placebo. The injections were given intravenously at home within the first 3 hours (within the first 2 hours in 26 of them), by doctors from Mobile care units.

[Repeated valvular replacements. Apropos of 64 cases].

In a series of 833 operations with implantation of 1011 prosthetic valves there were 64 reoperations on 44 patients, an incidence of 7.6%. In almost 50% of the cases, reoperation was motivated by desinsertion.

Hepatic proline after bile duct ligation in rats.

Since biliary hyperplasia of fascioliasis correlated with hepatic proline level, we examined the occurrence of a similar chemical stimulus during bile obstruction. Uptake of tritiated proline and glycine rose in both hepatocytes and a bile duct enriched cell fraction, following duct ligation in rats. The increased hepatic content of proline but not glycine suggests that proline has a role in post-obstructive biliary proliferation.

1H nuclear-magnetic-resonance studies of the molecular conformation of monomeric glucagon in aqueous solution.

Dilute aqueous solutions of glucagon were investigated by high-resolution 1H nuclear magnetic resonance at 360 MHZ. Monomeric glucagon was found to adopt predominantly an extended flexible conformation which contains, however, a local non-random spatial structure involving the fragment--Phe-22--Val-23--Gln-24--Trp-25--. This local conformation is preserved in the partial sequence 22--26 and could thus be characterized in detail.