A Colorectal Cancer 3D Bioprinting Workflow as a Platform for Disease Modeling and Chemotherapeutic Screening.

Colorectal cancer (CRC) is the third most common malignancy and has recently moved up to the second leading cause of death among carcinomas. Prognosis, especially for advanced diseases or certain molecular subtypes of CRC, remains poor, which highlights the urgent need for better therapeutic strategies. However, currently, as little as 0.

Refractive index investigation of poly(vinyl alcohol) films with TiO2 nanoparticle inclusions.

The refractive index (RI) of polymer nanocomposite of poly(vinyl alcohol) films with TiO(2) nanoparticle inclusions with low concentration up to 1.2 wt. % was investigated.

[Changes in the gastric mucosa of ulcer patients with a reflux syndrome].

To 254 patients with active peptic ulcer 302 esophageal and 438 gastric endoscopic biopsies were performed and studied histologically. The patients were classified into 2 groups with and without (control group) reflux syndrome. The histological examination established atrophic changes in the antral mucosa in 58.

[Actinomycosis of the liver].

A case of a 61-years-old man, diabetic, drinking systematically, with primary liver actinomycosis is presented. The clinical course was that of septic cholangiohepatitis leading to liver and renal failure and death of infectious-toxic shock. The diagnosis was proved at autopsy.

[Current aspects of the diagnosis and surgical treatment of reflux esophagitis].

For a period of 18 months (1986-1987) a total of 2595 fiber gastroscopies have been performed for different reasons. Reflux esophagitis (RE) was visualized in 436 of the patients undergone fiber gastroscopy (16.8 per cent), histologically verified in 64.

[Secretory gastric function and the development of reflux esophagitis in peptic ulcer].

129 patients with peptic ulcer in the acute stage of the disease were studied clinically, roentgenologically, endoscopically and morphologically. The patients were classified into two groups--with or without dyspeptic syndrome. The gastric acidity was examined by the fractionary titration method with pentagastrin as stimulant, Reflux-esophagitis was found in patients with hyperacidity as well as in patients with normal and hypoacidity.

[Endoscopic and morphological research on the changes in the esophageal mucosa in peptic ulcer combined with gastroesophageal reflux].

The endoscopic and morphological changes in esophagus of 71 patients with ulcer disease, accompanied with gastroesophageal reflux were studied, with following up of 10 histological signs in the multi-layer pavement epithelium of esophagus at the same time quantitatively evaluated. It has been established that morphological signs of esophagitis develop in case of gastroesophageal reflux among ulcer patients to 53.5%, being twice more frequent in duodenal ulcer than in gastric.