Linking preoperative and early intensive care unit data for prolonged intubation prediction.

Objectives: Prolonged intubation (PI) is a frequently encountered severe complication among patients following cardiac surgery (CS). Solely concentrating on preoperative data, devoid of sufficient consideration for the ongoing impact of surgical, anesthetic, and cardiopulmonary bypass procedures on subsequent respiratory system function, could potentially compromise the predictive accuracy of disease prognosis. In response to this challenge, we formulated and externally validated an intelligible prediction model tailored for CS patients, leveraging both preoperative information and early intensive care unit (ICU) data to facilitate early prophylaxis for PI.

A prognostic signature of fatty acid metabolism-related genes for predicting survival of gastric cancer patients.

To analyze the expression profile of fatty acid metabolism (FAM)-related genes, identify a prognostic signature, and evaluate its clinical value for gastric cancer (GC) patients. The mRNA expression profiles of 493 FAM-related genes were obtained from TCGA database. Differentially expressed genes (DEGs) between cancer and non-cancer samples were identified, and their relationships with overall survival (OS) of GC patients were evaluated.

Identifying a Risk Signature of Methylation-Driven Genes as a Predictor of Survival Outcome for Colon Cancer Patients.

Aberrant expression of gene is driven by its promoter methylation and is the key molecular basis of carcinogenic processes. This study aimed at identifying a risk signature of methylation-driven (MD) genes and evaluating its prognostic value for colon cancer (CC) patients. The expression profiles of methylation and mRNA in CC samples were obtained from the TCGA database, and the MethylMix algorithm was used to identify MD genes.

A novel miRNA-based signature as predictive tool of survival outcome of colorectal cancer patients.

It is great significance of identifying valuable biomarkers for early diagnosis and prognostic prediction of colorectal cancer (CRC) patients. This study aimed at developing and validating a miRNAs-based signature as prognostic tool for CRC patients. The miRNA expression profile of 624 CRC samples (613 tumor tissues and 11 normal tissues) was analyzed, and 523 differentially expressed miRNAs (DEmiRNAs) were identified, in which 191 were downregulated and 332 were upregulated.

Which is the appropriate surgical procedure for appendiceal adenocarcinoma: appendectomy, partial colectomy or right hemicolectomy?

Objective: The purpose of this study was to explore the appropriate surgical procedure and clinical decision for appendiceal adenocarcinoma.

Methods: A total of 1,984 appendiceal adenocarcinoma patients from 2004 to 2015 were retrospectively identified from the Surveillance, Epidemiology, and End Results (SEER) database. All patients were divided into three groups based on the extent of surgical resection: appendectomy (N = 335), partial colectomy (N = 390) and right hemicolectomy (N = 1,259).

Development and validation of a prognostic nomogram for rectal cancer patients who underwent surgical resection.

The purpose of this study was to develop and validate a nomogram model for the prediction of survival outcome in rectal cancer patients who underwent surgical resection. A total of 9,919 consecutive patients were retrospectively identified using the Surveillance, Epidemiology, and End Results (SEER) database. Significant prognostic factors were determined by the univariate and multivariate Cox analysis.

Apply Graph Signal Processing on NILM: An Unsupervised Approach Featuring Power Sequences.

As a low-cost demand-side management application, non-intrusive load monitoring (NILM) offers feedback on appliance-level electricity usage without extra sensors. NILM is defined as disaggregating loads only from aggregate power measurements through analytical tools. Although low-rate NILM tasks have been conducted by unsupervised approaches based on graph signal processing (GSP) concepts, enhancing feature selection can still contribute to performance improvement.

Mixed adenoneuroendocrine carcinoma originating from the appendix and colorectum: a comparative analysis of a large population-based database.

Purpose: As a rare gastrointestinal neoplasm, the demographic, clinicopathological, and prognostic characteristics of mixed adenoneuroendocrine carcinoma (MANEC) remain unclear. The purpose of this study was to evaluate its biological features, survival outcome, and prognostic factors.

Methods: From the Surveillance, Epidemiology, and End Results (SEER) database, we retrospectively reviewed clinicopathological and survival data of 513 patients who were histopathologically diagnosed with MANEC of the appendix and colorectum bettween 2004 and 2015.

Manipulating upconversion luminescence intensity in a single crystal particle with a waveguide structure.

Lanthanide (Ln)-doped upconversion luminescence (UCL) materials have attracted worldwide attention due to their unique photophysical characteristics. However, how to effectively improve their UCL efficiency has always been an important scientific issue. Here, we design and fabricate β-NaYF microtubes (MTs) with a natural hexagonal shape in the cross section and wedge shape on both top vertexes, which can be regarded as an optical waveguide.

Correction: Silence of cancer susceptibility candidate 9 inhibits gastric cancer and reverses chemoresistance.

[This corrects the article DOI: 10.18632/oncotarget.14871.

Study on discharge characteristics of fermentor and oak barrel washing wastewater from typical wineries in Ningxia, China.

Wine wastewater management is critical to the sustainable development of the wine industry. In this study, three wineries were selected with growing wine production scales of Ningxia. The number of fermentors and oak barrels washing wastewater were counted during the production period of 2019.

Central lymph node metastasis is predictive of survival in advanced gastric cancer patients treated with D2 lymphadenectomy.

Background: The number of positive lymph nodes, which was defined as "N stage", is mostly used to predict the survival of D2-resected gastric cancer patients, not the location. A "central lymph node" (CnLN) was defined by Ikoma et al., included common hepatic, celiac and proximal splenic artery LNs.

Nephronectin is a prognostic biomarker and promotes gastric cancer cell proliferation, migration and invasion.

Gastric cancer (GC) is a malignant disease with high incidence and mortality rates worldwide. Nephronectin (NPNT) was found to be dysregulated in some kinds of cancer. The goal of our study was to explore the expression profile of NPNT based on large numbers of GC samples with detailed clinicopathological and prognostic data from our institution and the data from a public database.

Different clinicopathologic features and prognostic significance of signet ring cell histology in early and locally advanced gastric cancer patients.

Background: Although many studies have evaluated the prognostic significance of signet ring cell (SRC) histology for gastric cancer (GC) patients, the results were conflicting. The objective of this study was to compare clinicopathologic characteristics between SRC type and other types, and evaluate its impact on survival outcome.

Methods: We retrospectively reviewed clinicopathologic and survival data of 1891 patients who underwent curative resection for GC.

Risk of lymph node metastasis and prognostic outcome in early gastric cancer patients with mixed histologic type.

Background: Whether early gastric cancer with mixed histologic type should be considered for endoscopic submucosal dissection (ESD) remains controversial. The objective of this study was to evaluate the risk of lymph node metastasis (LNM) and prognostic significance for early gastric cancer with mixed histologic type.

Methods: We retrospectively reviewed clinicopathologic and survival data of 302 patients who underwent surgical resection for early gastric cancer.

Different prognostic significance of signet ring cell histology for early and advanced gastric cancer patients: a systematic review and meta-analysis.

Objective: To review relevant studies and perform a meta-analysis to evaluate the prognostic significance of signet ring cell (SRC) histology for gastric cancer (GC) patients.

Methods: Systematic literature search was performed using PubMed and Embase databases. The relevant data were extracted and the association between SRC histology and survival outcome were evaluated using a fixed-effect or random-effect model.

Delaying adjuvant chemotherapy in advanced gastric cancer patients: Risk factors and its impact on survival outcome.

Adjuvant chemotherapy following the curative resection could improve the survival outcome of advanced gastric cancer (GC) patients. However, it is unclear whether delayed initiation of adjuvant chemotherapy had a negative impact on survival outcome in GC patients. The purpose of this study was to review current published literature about the impact of delaying adjuvant chemotherapy on survival outcome and summarize risk factors for delaying adjuvant chemotherapy.

Impact of Lymphovascular Invasion on Survival Outcome in Patients With Gastric Cancer.

Objectives: To evaluate the prognostic significance of lymphovascular invasion (LVI) for patients with gastric cancer (GC).

Methods: A total of 1,720 consecutive patients who underwent curative gastrectomy were retrospectively identified. The association between LVI and clinicopathologic characteristics was determined and its impact on survival outcome was evaluated.

Clinicopathological features, risk of lymph node metastasis and survival outcome of synchronous multiple early gastric cancer.

Objective: To determine clinicopathological features, risk of lymph node metastasis (LNM) and survival outcome in synchronous multiple early gastric cancer (MEGC) patients.

Methods: A total of 338 solitary early gastric cancer (SEGC) and 26 MEGC patients who underwent surgical resection were retrospectively reviewed. The clinicopathological features and predictive factors for MEGC patients were evaluated.

Clinicopathologic Features, Survival Outcome, and Prognostic Factors in Gastric Cancer Patients 18-40 Years of Age.

Whether young patients with gastric cancer (GC) had a distinct prognostic outcome from older patients remains controversial. The objective of this study was to investigate the clinicopathologic characteristics and prognostic factors of young GC patients and evaluate the survival outcome in comparison to their older counterparts. We retrospectively reviewed clinicopathologic and survival data of 2022 patients who underwent curative resection for GC.

The transformation and outcome of traditional cassava starch processing in Guangxi, China.

To improve the resource utilization, reduce the pollution generation, and increase the economic benefits of enterprises, a cleaner process to produce cassava starch was proposed based on potato starch processing, and it was applied to the transformation of a traditional cassava starch processing factory in the Guangxi Province in China. The transformation involves the implementation of several new techniques/facilities, including a rasper, horizontal centrifuge, and hydrocyclone. Based on the transformation, typical cassava starch factories in Guangxi were evaluated.

Perineural invasion as a predictive factor for survival outcome in gastric cancer patients: a systematic review and meta-analysis.

Aims: The prognostic significance of perineural invasion (PNI) for gastric cancer (GC) patients was under debate. This study aimed to review relevant studies and evaluate the impact of PNI on the survival outcome of GC patients.

Methods: Systematic literature search was performed using PubMed and Embase databases.

Comparison of short-term surgical outcome between 3D and 2D laparoscopy surgery for gastrointestinal cancer: a systematic review and meta-analysis.

Background: Three-dimensional (3D) laparoscopic surgery is becoming more popular with the development of laparoscopic devices. The objective of this study was to explore whether the 3D imaging system could improve surgical outcomes of laparoscopic surgery for gastrointestinal cancer compared with the 2D imaging system.

Methods: Systematic literature search was performed using PubMed and Embase databases and relevant data were extracted.

Does delayed initiation of adjuvant chemotherapy following the curative resection affect the survival outcome of gastric cancer patients: A systematic review and meta-analysis.

Background: Adjuvant chemotherapy(AC) following the curative resection could improve the survival outcome of advanced gastric cancer(GC) patients. However, there is no specific timing interval from radical surgery to initiation of AC. Whether delayed initiation of AC could affect the survival outcome of these patients remains unclear.

Impact of proximal resection margin involvement on survival outcome in patients with proximal gastric cancer.

Aim: The aim of this study was to evaluate the risk factors for proximal resection margin involvement and its impact on survival outcome in patients with proximal gastric cancer.

Methods: A total of 488 patients who underwent potentially curative resection for proximal gastric cancer were retrospectively reviewed. Clinicopathological characteristics and survival differences between patients with positive and negative resection margins were compared and prognostic factors were determined by Cox multivariate analysis.