LKAFFNet: A Novel Large-Kernel Attention Feature Fusion Network for Land Cover Segmentation.

The accurate segmentation of land cover in high-resolution remote sensing imagery is crucial for applications such as urban planning, environmental monitoring, and disaster management. However, traditional convolutional neural networks (CNNs) struggle to balance fine-grained local detail with large-scale contextual information. To tackle these challenges, we combine large-kernel convolutions, attention mechanisms, and multi-scale feature fusion to form a novel LKAFFNet framework that introduces the following three key modules: LkResNet, which enhances feature extraction through parameterizable large-kernel convolutions; Large-Kernel Attention Aggregation (LKAA), integrating spatial and channel attention; and Channel Difference Features Shift Fusion (CDFSF), which enables efficient multi-scale feature fusion.

Room-Temperature Salt Template Synthesis of Nitrogen-Doped 3D Porous Carbon for Fast Metal-Ion Storage.

The water-soluble salt-template technique holds great promise for fabricating 3D porous materials. However, an equipment-free and pore-size controllable synthetic approach employing salt-template precursors at room temperature has remained unexplored. Herein, we introduce a green room-temperature antisolvent precipitation strategy for creating salt-template self-assembly precursors to universally produce 3D porous materials with controllable pore size.

Peptide-Conjugated Probe Inducing Mitochondrial Dysfunction and Self-Reporting Cell Apoptosis by Aggregated Proteins.

Inducing and monitoring cell apoptosis in a real-time manner are crucial for evaluating the therapeutic effect of drugs and avoiding excessive treatment. Although promising advancements have been made to monitor cell apoptosis by assessing cell membrane integrity, the chronic compromise of cellular fitness caused by imbalance proteostasis is not visible and hard to be detected. As an indicator for cell apoptosis, imaging of aggregated proteins provides a new direction.

A Peptide-Conjugated Probe with Cleavage-Induced Morphological Change for Treatment on Tumor Cell Membrane.

Despite the promising advancements of in situ forming nanoassembly for the inhibition of tumor growth and metastasis, the lack of sufficient triggering sites and hardly controlling the forming position restrict their further developments. Herein, a smart transformable peptide-conjugated probe (DMFA) with enzyme cleavage-induced morphological change is designed for treatment on the tumor cell membrane. Specifically, after self-assembling into nanoparticles and anchoring on the cell membrane with sufficient interaction sites rapidly and stably, DMFA will be efficiently cleaved into α-helix forming part (DP) and β-sheet forming part (LFA) by overexpressed matrix metalloproteinase-2.

AIEgen-Peptide Bioprobes for the Imaging of Organelles.

Organelles are important subsystems of cells. The damage and inactivation of organelles are closely related to the occurrence of diseases. Organelles' functional activity can be observed by fluorescence molecular tools.

A mitochondria-targeted near-infrared fluorescent probe for imaging viscosity in living cells and a diabetic mice model.

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes with high selectivity and sensitivity, which was applied to detect the intracellular viscosity and image pancreatic tissue in a diabetic mouse model. Probe NIR-V provides an effective way to diagnose viscosity related diseases.

Heterostructure Engineering of Core-Shelled Sb@Sb O Encapsulated in 3D N-Doped Carbon Hollow-Spheres for Superior Sodium/Potassium Storage.

In this work, the core-shelled Sb@Sb O heterostructure encapsulated in 3D N-doped carbon hollow-spheres is fabricated by spray-drying combined with heat treatment. The novel core-shelled heterostructures of Sb@Sb O possess a mass of heterointerfaces, which formed spontaneously at the core-shell contact via annealing oxidation and can promote the rapid Na /K transfer. The density functional theory calculations revealed the mechanism and significance of Na/K-storage for the core-shelled Sb@Sb O heterostructure, which validated that the coupling between the high-conductivity of Sb and the stability of Sb O can relieve the shortcomings of the individual building blocks, thereby enhancing the Na/K-storage capacity.

A new mitochondrion targetable fluorescent probe for carbon monoxide-specific detection and live cell imaging.

A new mitochondrion targetable molecular probe for carbon monoxide (CO)-specific detection based on palladium-free mediated opening of spirolactam was designed. The turn-on red fluorescence caused by CO enables a safe and powerful method for unravelling the function of CO in biological systems to be established.

Sensing and imaging of mitochondrial viscosity in living cells using a red fluorescent probe with a long lifetime.

A red fluorescent probe (Mito-V) with a long lifetime was designed to monitor viscosity changes with high selectivity and sensitivity. The fluorescence intensity and lifetime of Mito-V displayed a good relationship with the viscosity value, and Mito-V was successfully applied to sensing mitochondrial viscosity changes in living cells under different biological processes.

Intracellular endogenous glutathione detection and imaging by a simple and sensitive spectroscopic off-on probe.

Glutathione (GSH) exhibits many cellular functions in human pathologies. A sensitive and simple method capable of assaying GSH would be useful to understand the mechanism of GSH-related diseases. In this study, a new colorimetric and fluorescent off-on probe, 3-oxo-3H-phenoxazin-7-ylthiophene-2-carboxylate, is constructed, synthesized and applied to determine fluctuations in intracellular GSH levels selectively and sensitively.

Cobalt Oxide Porous Nanofibers Directly Grown on Conductive Substrate as a Binder/Additive-Free Lithium-Ion Battery Anode with High Capacity.

In order to reduce the amount of inactive materials, such as binders and carbon additives in battery electrode, porous cobalt monoxide nanofibers were directly grown on conductive substrate as a binder/additive-free lithium-ion battery anode. This electrode exhibited very high specific discharging/charging capacities at various rates and good cycling stability. It was promising as high capacity anode materials for lithium-ion battery.