Publications by authors named "Bobo Yang"

Article Synopsis
  • Acrylonitrile (AN) is an organic compound that can cause neurotoxicity, but the mechanism behind this is not fully understood; HIF-1α plays a crucial role in cellular response to low oxygen levels and may help with survival.
  • In lab studies, AN reduced the levels of HIF-1α and other proteins associated with cell survival and function, leading to mitochondrial damage and increased cell death.
  • Treatment that activates HIF-1α (like cobalt chloride) showed protective effects against neurotoxicity, suggesting that enhancing this pathway could be a potential strategy for mitigating the harmful effects of AN exposure.
View Article and Find Full Text PDF
Article Synopsis
  • The study introduces a fast, non-invasive method for identifying Baijiu, a traditional Chinese liquor, using the Tyndall effect and chemometrics.
  • By shining a laser on Baijiu and analyzing the resulting light path, researchers can determine important characteristics like flavor, age, and possible adulteration.
  • Various analytical techniques, including PCA, LDA, and HCA, were used to establish correlations between the light properties and flavor compounds, enabling quick identification of Baijiu's quality and composition.
View Article and Find Full Text PDF

Charge transfer efficiencies in all-inorganic lead halide perovskite nanocrystals (NCs) are crucial for applications in photovoltaics and photocatalysis. Herein, CsPbBr NCs with different sizes are synthesized by varying the ligand contents of didodecyl dimethylammonium bromide at room temperature. Adding benzoquinone (BQ) molecules leads to a decrease in the PL intensities and PL decay times in NCs.

View Article and Find Full Text PDF

Manganese (Mn) overexposure has been associated with the development of neurological damage reminiscent of Parkinson's disease, while the underlying mechanisms have yet to be fully characterized. This study aimed to investigate the mechanisms leading to injury in dopaminergic neurons induced by Mn and identify novel treatment approaches. In the in vivo and in vitro models, ICR mice and dopaminergic neuron-like PC12 cells were exposed to Mn, respectively.

View Article and Find Full Text PDF
Article Synopsis
  • An epoxy resin thermally conductive adhesive is developed using spherical alumina as a filler, and its properties are significantly influenced by curing conditions, specifically at a temperature of 150 °C for 2.5 hours, resulting in improved performance.
  • Curing agents with superbranched structures enhance the toughness of the adhesive and can increase shear strength by up to 307%, while higher curing temperatures raise both the glass transition and decomposition temperatures.
  • The study highlights that adjusting curing parameters changes the fracture morphology from brittle to ductile, affecting the thermal conductivity and stability of the epoxy resin adhesive.
View Article and Find Full Text PDF

Metal halide perovskites are particularly emerging for optoelectronic applications in light-emitting diodes, photodetectors, and solar cells due to their flourishing photophysical properties. However, the poor stability of three-dimensional (3D) lead halide perovskite nanocrystals (NCs) significantly hampers their optoelectronics and photovoltaics applications. Embedding 3D perovskites into zero-dimensional (0D) perovskite crystals and doping ions of appropriate elements into host lattices provide effective approaches to improve the stability and optical-electronic performance.

View Article and Find Full Text PDF

Manipulation of persistent charges in semiconductor nanostructure is the key point to obtain quantum bits towards the application of quantum memory and information devices. However, realizing persistent charge storage in semiconductor nano-systems is still very challenge due to the disturbance from crystal defects and environment conditions. Herein, the two-photon persistent charging induced long-lasting afterglow and charged exciton formation are observed in CsPbBr perovskite nanocrystals (NCs) confined in glass host with effective lifetime surpassing one second, where the glass inclosure provides effective protection.

View Article and Find Full Text PDF

Light-emitting diodes (LEDs) were the best artificial light source for plant factories. Red light-emitting diodes (LEDs, R) and blue light-emitting diodes (LEDs, B) were used to obtain different light intensities of uniform spectra, and the greenhouse environment was considered as a comparison. The results showed that root dry weight, shoot dry weight and stem diameter were superior in plant growth under 240 μmolm-2s-1, additionally, the Dixon Quality Index (DQI) was also best.

View Article and Find Full Text PDF

Epoxy thermal conductive adhesives with high thermal conductivity and dynamic mechanical properties are important thermally conductive materials for fabricating highly integrated electronic devices. In this paper, micro-Al2O3 is used as a thermally conductive filler for the epoxy resin composite and investigated the effect of micron-sized alumina particle size on the thermal conductivity and dynamic mechanical property of epoxy resin by the transient planar hot plate method and DMA (Dynamic mechanical analysis). The experimental results show that with the same amount of alumina filling, the thermal conductivity and Tg (glass transition temperature) of epoxy/Al2O3 composite material decrease with the increase of alumina particle size.

View Article and Find Full Text PDF

Metastasis-associated in colon cancer 1 (MACC1) is an oncogene associated with the progression and metastasis of many solid cancer entities. High expression of MACC1 is found in colorectal cancer (CRC) tissues. So far, the role of MACC1 in CRC cell pyroptosis and resistance to irinotecan is unclear.

View Article and Find Full Text PDF

Perovskite microcrystals have attracted wide attention and have been applied in extensive optical applications. The CsPbX perovskite poses a great threat to the environment due to the presence of lead (Pb), and there is an urgent need to improve the photoluminescence quantum yield. Therefore, a lead-free perovskite microcrystal material CsRbAgInBiCl with a high photoluminescence quantum yield (PLQY) was synthesized by a convenient hydrothermal method, with comprehensive characterization of both the structure and optical performance at varying Rb ratios.

View Article and Find Full Text PDF

Cytochrome P450 2E1 (CYP2E1) plays an essential role in the susceptibility to acute acrylonitrile (AN)-induced toxicity. Here, we investigated the toxicity and mechanism of AN in fasting mice and potential underlying mechanisms. Convulsions, loss of righting reflex, and death 4 h after AN treatment were observed and recorded for each group of mice.

View Article and Find Full Text PDF

Background: Hydrogen sulfide (HS), as the third gasotransmitter participates in both cellular physiological and pathological processes, including chemical-induced injuries. We recently reported acute acrylonitrile (AN) treatment inhibited endogenous HS biosynthesis pathway in rat and astrocyte models. However, there is still no evidence to address the correlation between endogenous HS and sub-chronic AN exposure.

View Article and Find Full Text PDF

Objective: Ferroptosis is an iron-dependent nonapoptotic form of cell death, characterized by iron accumulation and lipid peroxidation. However, the role of ferroptosis in methylmercury (MeHg)-induced cytotoxicity has yet to be fully characterized. The purpose of this study was to investigate the role of ferroptosis in MeHg-induced cytotoxicity in both brain and liver cells.

View Article and Find Full Text PDF
Article Synopsis
  • InP quantum dots (QDs) are being explored for optoelectronic applications due to their non-toxic nature and good performance.
  • The study reveals how interfacial structures in InP/ZnS QDs are influenced by anion exchange during the shell-growth stage, specifically highlighting the roles of halogen ions and shelling temperature.
  • Higher shelling temperatures and the presence of iodide ions lead to improved optical properties, resulting in highly efficient blue-emissive QDs with a wavelength of 473 nm and a quantum yield of around 50%.
View Article and Find Full Text PDF

Manganese (Mn) is an essential mineral, but excess exposure can cause dopaminergic neurotoxicity. Restless legs syndrome (RLS) is a common neurological disorder, but the etiology and pathology remain largely unknown. The purpose of this study was to identify the role of Mn in the regulation of an RLS genetic risk factor BTBD9, characterize the function of BTBD9 in Mn-induced oxidative stress and dopaminergic neuronal dysfunction.

View Article and Find Full Text PDF

Metal halide perovskite nanostructures have sparked intense research interest due to their excellent optical properties. In recent years, although the green and red perovskite light-emitting diodes (PeLEDs) have achieved a significant breakthrough with the external quantum efficiency exceeding 20%, the blue PeLEDs still suffer from inferior performance. Previous reviews about blue PeLEDs focus more on 2D/quasi-2D or 3D perovskite materials.

View Article and Find Full Text PDF

Acrylonitrile (AN) is a known animal carcinogen and suspected human carcinogen. Recently, occupational exposure to AN has considerably increased. Previously, we demonstrated that streptozotocin-induced diabetes potentiates AN-induced acute toxicity in rats and that the induced cytochrome P450 2E1 (CYP2E1) is responsible for this effect.

View Article and Find Full Text PDF

Metals are actively involved in multiple catalytic physiological activities. However, metal overload may result in neurotoxicity as it increases formation of reactive oxygen species (ROS) and elevates oxidative stress in the nervous system. Mitochondria are a key target of metal-induced toxicity, given their role in energy production.

View Article and Find Full Text PDF

Hydrogen sulfide (HS) as the third gasotransmitter molecule serves various biological regulatory roles in health and disease. Acrylonitrile (AN) is a common occupational toxicant and environmental pollutant, causing brain and liver damage in mammals. The biotransformation of AN is dependent-upon reduced glutathione (GSH), cysteine and other sulfur-containing compounds.

View Article and Find Full Text PDF

Dipicolinic acid (DPA) is employed as a significant biomarker to detect Bacillus anthracis, which can do serious damages to the health of human beings. Hence, it is crucial to develop a fast and highly efficient strategy for DPA monitoring. In this work, based on silicon nanoparticles (Si NPs) and terbium metal-organic frameworks (Tb-MOFs), a hybrid structure (Si NPs/Tb-MOFs) as a novel dual-emitting fluorescence probe was fabricated for ratiometric detection of DPA, where blue light-emitting Si NPs (Ex: 280 nm; Em: 422 nm) are encapsulated into green light-emitting Tb-MOFs (Ex: 280 nm; Em: 547 nm).

View Article and Find Full Text PDF

Cutaneous wound healing is pivotal for human skin to regain barrier function against pathogens. MicroRNAs (miRNAs) have been found to play regulatory roles in wound healing. However, the mechanism of miRNA regulation remains largely unknown.

View Article and Find Full Text PDF

Single-phased and dual-emissive nanocrystals with broad emission are attractive fluorescent materials for optoelectronic devices due to their unique properties. Until now, the effect of different metallic cations and inorganic anions on III-V group quantum dots (QDs) concerning luminescence features and crystalline growth has been less explored. In this work, dual-emissive InP/ZnS QDs single-doped with transition-metal compounds (Cu, Ag, or Mn) are synthesized to compare their optical and morphological properties.

View Article and Find Full Text PDF

Hypoxia-inducible factor 1 (HIF-1) is a critical nuclear transcription factor for adaptation to hypoxia; its regulatable subunit, HIF-1α, is a cytoprotective regulatory factor. We examined the effects of methylmercury (MeHg) in rat adrenal pheochromocytoma (PC12) cells and the rat hepatocyte cell line BRL. MeHg treatment led to time- and concentration-dependent toxicity in both lines with statistically significant cytotoxic effects at 5 μM and 10 μM in PC12 and BRL, respectively, at 0.

View Article and Find Full Text PDF

A new yellow long afterglow luminescent material CaSnO:Dy was prepared by the solid state method at 1350 °C. The yellow LLP (long-lasting phosphorescent) material CaSnO:Dy was prepared by co-doping alkaline ions (K and Na) and investigated using an X-ray diffractometer (XRD), photoluminescence spectrometer, afterglow meter and thermoluminescence spectrometer. The excitation and emission spectra showed an excitation peak at 350 nm and an emission peak at 573 nm.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessiontupg3uuof2jgm017ujva14gd3gkke55v): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once