Design and synthesis of glycofullerene derivatives as novel photosensitizer for potential application in PDT to treat cancer.

Cancer is one of the most aggressive diseases known to humanity, characterized by low survival rates and poor prognoses. Currently, platinum-based anticancer drugs and traditional photosensitizers used in photodynamic therapy (PDT) are the most widely employed treatment modalities. However, the platinum-based medications, particularly cisplatin, the most commonly used agent, have several drawbacks.

Mapping the susceptibility to freeze-thaw deterioration and regionalization of freeze-thaw environments of earthen sites in China: A preliminary study.

Earthen sites in China are widely exposed to freeze-thaw environments. There is a lack of knowledge about the spatial distribution patterns of freeze-thaw deterioration and environments, as well as preventive conservation strategies and subsequent refined research on the freeze-thaw deterioration of earthen sites. In this study, the freeze-thaw deterioration process of earthen sites was divided into two periods.