[Blood serum glycoproteins in men exposed to carbon disulfide].

In 48 men occupationally exposed to CS2 the following glycoproteins were estimated in blood serum, using radial immunodiffusion on M-Partigen plates: alpha1-acid glycoprotein, alpha1-antitrypsin, alpha2-HS-glycoprotein, alpha2-macroglobulin, Gc glycoprotein, hemopexin, haptoglobin, ceruluplasmin and beta2-glycoprotein I. The studies indicated a highly statistically significant increase of: alpha1-acid--glycoprotein and Gc glycoprotein, and decrease of: alpha1-antitrypsins, alpha2-HS--glycoprotein and beta2-glycoprotein. The level of the remaining glycoproteins was normal.

Immunologic evaluation of beta-lipoprotein antigen in the serum of men exposed to carbon disulfide over protracted periods of time.

beta-Lipoprotein was isolated by the precipitation method from collective serum of 47 men aged 27-49 years (mean 42-1 years) exposed to carbon disulfide during work over long periods of time. Significantly elevated levels of serum beta-lipoprotein, clinical and polycardiographic symptoms were found in 85-1% of subjects. Antibodies to beta-lipoprotein obtained by immunizing rabbits intravenously were compared with similar antibodies in healthy subjects by double immunodiffusion in agar and by the passive hemagglutination test.