Publications by authors named "Bobbe Thomas"

Background: Serious car seat installation errors occur at high rates in infants and children. These errors significantly increase the risk of child injury in a motor vehicle crash, and few interventions have addressed the challenge longitudinally.

Methods: This was a pilot randomised controlled feasibility trial of virtual car seat safety checks for caregivers of newborns recruited from an urban newborn nursery.

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Article Synopsis
  • The study investigated the role of inflammation in children with seizures by analyzing inflammatory cytokines in their blood and saliva and comparing them to healthy controls, as well as assessing potential associations with viral infections (HHV-6 and EBV).
  • Results indicated that children with seizures had significantly higher levels of various inflammatory cytokines compared to controls, with specific cytokine levels linked to the frequency and duration of seizures.
  • The findings suggested that neuroinflammatory pathways are activated differently in seizure patients, but these changes did not appear to be related to the presence or load of viral infections.
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Enrollment of patients in sickle cell intervention trials has been challenging due to difficulty in obtaining consent from a legal guardian and lack of collaboration between emergency medicine and hematology. We utilized education and preconsent in a pediatric multisite sickle cell intervention trial to overcome these challenges. Overall, 48 patients were enrolled after being preconsented.

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