HBeAg-negative chronic hepatitis B patients and inactive carriers show overlapping lab and serology results, complicating diagnosis.
A study of 109 patients identified 56 as inactive carriers and 53 as having active chronic hepatitis, revealing distinct mean levels of ALT, HBV DNA, and qHBsAg between the groups.
Combining the analysis of ALT, HBV DNA, and qHBsAg is essential for accurately distinguishing between inactive carriers and those with active HBeAg-negative chronic hepatitis B.