Publications by authors named "Bob Okeyo"

Article Synopsis
  • High-flow nasal cannula (HFNC) is being explored as a respiratory support option in rural Kenya for children with acute lower respiratory diseases, marking its first reported use in sub-Saharan Africa.
  • A feasibility study at Kijabe Hospital found no significant differences in clinical outcomes between patients using HFNC and historical controls, despite challenges such as technical issues with equipment and increased workload for staff.
  • The small sample size and variability in patient conditions limit generalizability to other low- and middle-income countries, indicating that while HFNC can be useful, more research is needed to address implementation challenges.
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Background: Kenya's neonatal mortality rate remains unacceptably high, at 22 deaths per 1000 live births, with a third of those attributable to prematurity. Respiratory distress syndrome (RDS) is the single most important cause of morbidity and mortality in the premature neonate. Continuous positive airway pressure (CPAP) is a proven modality of therapy but is rarely used in low-resource settings.

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