Potentially useful markers for desmoplastic melanoma: an analysis of KBA.62, p-AKT, and ezrin.

Desmoplastic melanoma (DM) represents only a small portion of newly diagnosed melanoma cases but can be a significant diagnostic challenge for dermatopathologists. Immunohistochemical stains are often useful to confirm the diagnosis; however, DM is notorious for not expressing most of the melanocytic markers other than S100. Recent studies have suggested several new markers, which may be promising in the diagnosis of DM.

Pathology of late-onset anthracycline cardiomyopathy.

Introduction: Anthracyclines are known to have acute cardiotoxicity. Anthracycline-induced dilated cardiomyopathy may have late onset and present years after administration of the drug. Several studies have described the clinical findings in patients with late-onset cardiomyopathy, including electrocardiography, exercise testing, echocardiography, and histological findings in endomyocardial biopsies; however, there is little information on the pathological changes that are found in explanted or autopsy hearts.

Myoepithelioma with melanocytic colonization (melanocytic myoepithelioma): a case report.

Mixed tumors of the salivary glands and the skin (also known as chondroid syringomas) contain epithelial and myoepithelial components in a chondroid to myxoid stroma. Lesions that are composed solely of cells with myoepithelial differentiation are known as myoepitheliomas. These tumors have been well described in the salivary glands and many other sites, and within the past decade, cutaneous myoepitheliomas have been described as well.