Gut Commensal Barnesiella Intestinihominis Ameliorates Hyperglycemia and Liver Metabolic Disorders.

Recent studies have highlighted the role of the gut microbiota in type 2 diabetes (T2D). Improving gut microbiota dysbiosis can be a potential strategy for the prevention and management of T2D. Here, this work finds that the abundance of Barnesiella intestinihominis is significantly decreased in the fecal of T2D patients from 2-independent centers.

O-GlcNAc transferase promotes vascular smooth muscle calcification through modulating Wnt/β-catenin signaling.

Vascular calcification (VC), associated with high cardiovascular mortality in patients with chronic kidney disease (CKD), involves osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs). O-GlcNAcylation, a dynamic post-translational modification, is closely linked to cardiovascular diseases, including VC. However, the exact role and molecular mechanism of O-GlcNAc signaling in abnormal mineral metabolism-induced VC remain unclear.

The synthesis of cyclometalated platinum(II) complexes with benzoaryl-pyridines as C^N ligands for investigating their photophysical, electrochemical and electroluminescent properties.

A series of (C^N)Pt(acac)-type complexes has been successfully synthesized with a benzo[b]furan, benzo[b]thiophene, benzo[b]selenophene, or benzo[b]tellurophene group in the benzoaryl-pyridine ligand. Using X-ray crystallography, the chemical structures of the complexes with benzo[b]selenophene and benzo[b]tellurophene groups have been clearly revealed. The photophysical, electrochemical, and electroluminescent (EL) behaviors of these (C^N)Pt(acac)-type complexes have been fully characterized.

Highly Efficient Deep-Red Organic Light-Emitting Devices Based on Asymmetric Iridium(III) Complexes with the Thianthrene 5,5,10,10-Tetraoxide Moiety.

Highly efficient deep-red organic light-emitting devices (OLEDs) are indispensable for developing high-performance red-green-blue (RGB) displays and white OLEDs (WOLEDs). However, the shortage of deep-red emitters with high photoluminescence quantum yields (PLQYs) and balanced charge injection/transport abilities has severely restricted the performance of deep-red OLEDs. Herein, we design and synthesize four efficient emitters by combining the isoquinoline group with the thianthrene 5,5,10,10-tetraoxide group.

Asymmetric Heteroleptic Ir(III) Phosphorescent Complexes with Aromatic Selenide and Selenophene Groups: Synthesis and Photophysical, Electrochemical, and Electrophosphorescent Behaviors.

With the aim of evaluating the potential of selenium-containing groups in developing electroluminescent (EL) materials, a series of asymmetric heteroleptic Ir(III) phosphorescent complexes (Ir-Se0F, Ir-Se1F, Ir-Se2F, and Ir-Se3F) have been synthesized by using 2-selenophenylpyridine and one ppy-type (ppy = 2-phenylpyridine) ligand with a fluorinated selenide group. To the best of our knowledge, these complexes represent unprecedented examples of asymmetric heteroleptic Ir(III) phosphorescent emitters bearing selenium-containing groups. Natural transition orbital (NTO) analysis based on optimized geometries of the first triplet state (T) have shown that the phosphorescent emissions of these Ir(III) complexes dominantly show π-π* features of the 2-selenophenylpyridine ligand with slight metal to ligand charge transfer (MLCT) contribution.

Erratum: Diarylboron-Based Asymmetric Red-Emitting Ir(III) Complex for Solution-Processed Phosphorescent Organic Light-Emitting Diode with External Quantum Efficiency above 28.

[This corrects the article DOI: 10.1002/advs.201701067.

Diarylboron-Based Asymmetric Red-Emitting Ir(III) Complex for Solution-Processed Phosphorescent Organic Light-Emitting Diode with External Quantum Efficiency above 28.

Organic light-emitting diodes (OLEDs) are one of the most promising technologies for future displays and lighting. Compared with the blue and green OLEDs that have achieved very high efficiencies by using phosphorescent Ir(III) complexes, the red OLEDs still show relatively low efficiencies because of the lack of high-performance red-emitting Ir(III) complexes. Here, three highly efficient asymmetric red-emitting Ir(III) complexes with two different cyclometalating ligands made by incorporating only one electron-deficient triarylboron group into the nitrogen heterocyclic ring are reported.

Highly efficient electroluminescent Pt ppy-type complexes with monodentate ligands.

Functional Pt ppy-type complexes (ppy = 2-phenylpyridine anion) with pyridine and chloride monodentate ligands are prepared, which show high electroluminescence efficiencies.

High Triplet Energy Level Achieved by Tuning the Arrangement of Building Blocks in Phosphorescent Polymer Backbones for Furnishing High Electroluminescent Performances in Both Blue and White Organic Light-Emitting Devices.

A high triplet energy level (E) of ca. 2.83 eV has been achieved in a novel polymer backbone through tuning the arrangement of two kinds of building blocks, showing enhanced hole injection/transporting capacity.

Bis-Zn salphen complexes bearing pyridyl functionalized ligands for efficient organic light-emitting diodes (OLEDs).

Inspired by the emissive features of Zn complexes based on bis-Schiff base ligands, bis-Zn salphen complexes bearing pyridyl functionalized ligands have been successfully synthesized. Their photophysical features, electrochemical behavior and electroluminescent (EL) properties have been investigated in detail. The functionalized bis-Zn salphen complexes can exhibit high thermal stability up to 417 °C, and their photoluminescence (PL) spectra show a maximal emission wavelength peak at ca.

Pyrimidine-Based Mononuclear and Dinuclear Iridium(III) Complexes for High Performance Organic Light-Emitting Diodes.

Containing two nitrogen atoms, the electron-deficient pyrimidine ring has excellent coordinating capability with transition metal ions. However, compared with the widely used pyridine ring, applications of the pyrimidine ring in phosphorescent Ir(III) complexes are rare. In this research, two highly emissive pyrimidine-based mononuclear Ir(III) complexes and their corresponding dinuclear Ir(III) complexes were prepared with a simple one-pot reaction.