Anxiety disturbs the blood plasma metabolome in acute coronary syndrome patients.

Coronary heart disease (CHD) is the result of a complex metabolic disorder caused by various environmental and genetic factors, and often has anxiety as a comorbidity. Rupture of atherosclerotic plaque in CHD patients can lead to acute coronary syndrome (ACS). Anxiety is a known independent risk factor for the adverse cardiovascular events and mortality in ACS, but it remains unclear how stress-induced anxiety behavior impacts their blood plasma metabolome and contributes to worsening of CHD.

Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.

Background: The outbreak of a new coronavirus, first reported in Wuhan, China, is spreading around the world. Information on the characteristics of children with Coronavirus Disease 2019 (COVID-19) is limited.

Methods: In this retrospective study, we recruited 10 children infected with SARS-COV-2 from January 27 to March 10, 2020, in Changsha, China.

Electronic medical record-based model to predict the risk of 90-day readmission for patients with heart failure.

Background: Several heart failure (HF) risk models exist, however, most of them perform poorly when applied to real-world situations. This study aimed to develop a convenient and efficient risk model to identify patients with high readmission risk within 90 days of HF.

Methods: A multivariate logistic regression model was used to predict the risk of 90-day readmission.

[Antibiotic resistance of gram-negative Bacillis isolated from children with bronchopneumonia].

Objective: To study the distribution and antibiotic resistance of gram-negative pathogens isolated from children with bronchopneumonia.

Methods: The distribution and the results of susceptibility tests of 272 strains of gram-negative Bacillis isolated from children with bronchopneumonia during 2009 were analyzed.

Results: Among the isolates, the common pathogens were Klebsiella pneumoniae and Escherichia coli.