Publications by authors named "Bo-Wen Zhu"
Profiling of gene fusion involving targetable genes in Chinese gastric cancer.
World J Gastrointest Oncol
August 2022
Background: Approximately half of all new cases of gastric cancer (GC) and related deaths occur in China. More than 80% of patients with GC are diagnosed at an advanced stage, which results in poor prognosis. Although -directed therapy and immune checkpoint inhibitors have been somewhat successful, new drugs are still needed for the treatment of GC.
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- The incidence of HIV-1 among men who have sex with men (MSM) is increasing in China, particularly in Jiangsu Province, necessitating exploration into the virus's genetic diversity.
- Researchers studied MSM who were recently infected with HIV-1 between 2012 and 2015, analyzing demographic data and conducting phylogenetic tests to assess the strains present.
- The findings revealed a high diversity of HIV-1 subtypes, notably CRF01_AE and CRF07_BC, with the CRF01_AE strain appearing in the region earlier than CRF07_BC, highlighting significant evolutionary patterns and clusters of infection.
Two new mononuclear Fe(II) complexes, [FeL1(NCBH3)2] (1) and [FeL2(CN)2]·3H2O (2) (L1 = N,N'-bis(2-pyridylmethyl)-1,2-ethanediamine, L2 = N-(2-pyridylmethyl)-N'-(2-pyridylmethylene)-1,2-ethanediamine) were synthesized from the same starting solution under different atmospheric conditions. Complex 1 was isolated under an N2 atmosphere with an expected molecular structure, namely a tetradentate L1 ligand and two NCBH3(-) co-ligands wrapping an iron(ii) ion. It exhibits a gradual spin crossover centered around 355 K, as confirmed by X-ray crystallography, magnetic, DSC and Mössbauer studies.
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