Publications by authors named "Bo-Ren Jiang"
Article Synopsis
- Thyroid hormones impact how the pancreas secretes insulin in response to glucose, and this study investigates their effects on beta-cell function in people with normal thyroid levels and those with untreated type 2 diabetes (T2DM).
- A total of 5089 participants were included, revealing that untreated T2DM patients had higher levels of thyroxine compared to the general population, but a lower ratio of T3 to T4.
- The study found that higher free thyroxine (FT4) levels negatively correlated with beta-cell function (measured by HOMA-β), suggesting that even within normal thyroid hormone ranges, FT4 plays a significant role in pancreatic function.
Purpose: To determine whether ectopic thyroid had the same computed tomography (CT) value as orthotopic thyroid.
Methods: Twenty-one patients with 23 ectopic thyroids and 23 controls with orthotopic thyroids underwent CT scans and were included in this retrospective study. The CT images were reviewed in a blinded fashion by two radiologists.
Background: 17α-Hydroxylase/17,20-lyase deficiency (17OHD) caused by a mutation in the CYP17A1 gene is characterized by hypertension, hypokalemia, and abnormal development of the genitalia. The majority of CYP17A1 mutations are located in the coding sequence, and several intronic splicing site mutations have been reported.
Objective: A 2.