Publications by authors named "Bo-Qiang Hu"
Article Synopsis
- Research on gene rearrangements has led to targeted cancer therapies, particularly by identifying oncogenic fusion proteins in gliomas.
- In a study involving 272 gliomas, certain fusion transcripts were found more frequently in high-grade gliomas, especially after treatment with radiation or temozolomide.
- The study highlights a specific fusion, PTPRZ1-MET (ZM), that is associated with worse outcomes in patients and is linked to increased cell migration and invasion in glioblastoma cells.
