Introduction: The MHC-peptide interaction has a subtle influence on host resistance to virus. This paper aims to study the relationship between MHC-peptide interaction and MHC-related virus-resistance.
Methods: By 3D homology modeling, the structure of chicken BF2 molecule BF2*0201 (PDB code: 4d0d) was studied and compared with the known structures of BF2 molecule BF2*0401 (PDB code: 4e0r) to elucidate the characteristics of BF2*0201-binding antigenic peptides.
Comp Biochem Physiol Part D Genomics Proteomics
March 2020
Nilaparvata lugens is a serious threat to rice growth. Glycogen metabolism is one of the important physiological processes of insects, which is mainly regulated by glycogen synthase (GS) and glycogen phosphorylase (GP). In the present study, trehalose content was significantly reduced at 72 h after NlGP and NlGS knockdown, whereas glucose content was significantly increased at both 48 h and 72 h after GS knockdown.
View Article and Find Full Text PDFIntermittent food shortages are commonly encountered in the wild. During winter or starvation stress, mammals often choose to hibernate while insects-in the form of eggs, mature larvae, pupae, or adults opt to enter diapause. In response to food shortages, insects may try to find sufficient food to maintain normal growth and metabolism through distribution of populations or even migration.
View Article and Find Full Text PDFAkirin is an essential nuclear protein involved in the regulation of NF-κB signaling pathway. In most invertebrates, Akirin regulates NF-κB-related Imd and Toll pathways, however, in , it only controls the Imd pathway, whereas its role in NF-κB signaling pathway in other insect species is unclear. In the present study, we used white-backed planthopper as a model to investigate the functional activity of Akirin in insects.
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