Synopsis of recent research by authors named "Bo-Kai Wu"
- Bo-Kai Wu's research primarily focuses on the molecular mechanisms underlying neurodegenerative disorders, particularly the role of tau proteins and neurotoxicity, utilizing zebrafish models to study the effects of various pharmacological agents and genetic factors on neuronal health.
- His studies have explored the neuroprotective effects of epicatechin from Tripterygium wilfordii and various signaling factors that can alleviate neuronal death induced by tau protein expression, highlighting the potential therapeutic strategies for tauopathies and Alzheimer's disease.
- Additionally, Wu has characterized the zebrafish Rtn-4/Nogo genes and their alternative promoters, contributing to the understanding of neuroregenerative pathways, and investigated the expression patterns of synuclein family genes, deepening insights into neurodevelopment and related pathologies.