Publications by authors named "Bo-Chun Wu"

Article Synopsis
  • Zinc oxide nanoparticles (ZnO NPs) are used in various applications, but their behavior in living organisms is not well understood, leading this study to create a pharmacokinetic model for their interactions in mice.
  • The study estimated key parameters such as partition coefficients and elimination rates for different sizes of ZnO NPs and compared them to zinc nitrate, discovering that smaller ZnO NPs have a higher tendency to accumulate in tissues, especially the lungs.
  • The findings suggest that after a certain period, ZnO NPs may decompose into zinc ions, indicating the need for careful consideration regarding the potential long-term exposure effects of smaller ZnO NPs.
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Inhalation of silica (SiO2) in occupational exposures can cause pulmonary fibrosis (silicosis), lung function deficits, pulmonary inflammation, and lung cancer. Current risk assessment models, however, cannot fully explain the magnitude of silica-induced pulmonary disease risk. The purpose of this study was to assess human health risk exposed to airborne silica dust in Taiwan ceramics manufacturing.

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