Synopsis of recent research by authors named "Bo-Bo Yang"
- Bo-Bo Yang's recent research focuses on the role of MACC1 and Gasdermin-E (GSDME) in regulating the resistance of colorectal cancer cells to the chemotherapeutic agent irinotecan.
- The study highlights that MACC1, an oncogene linked to cancer progression and metastasis, has high expression levels in colorectal cancer tissues, suggesting a critical role in cancer cell survival mechanisms.
- Preliminary findings indicate that the interaction between MACC1 and GSDME may influence pyroptosis, a form of programmed cell death, thereby affecting the sensitivity of colorectal cancer cells to irinotecan treatment.