Deep learning-mediated prediction of concealed accessory pathway based on sinus rhythmic electrocardiograms.

Background: Concealed accessory pathway (AP) may cause atrial ventricular reentrant tachycardia impacting the health of patients. However, it is asymptomatic and undetectable during sinus rhythm.

Methods: To detect concealed AP with electrocardiography (ECG) images, we collected normal sinus rhythmic ECG images of concealed AP patients and healthy subjects.

[Cathepsin B promoted the apoptosis of vascular smooth muscle cells as induced by tumor necrosis factor-α].

Objective: To establish the cathepsin B over-expression group and cathepsin B gene-silencing group so as to investigate whether cathepsin B was capable of promoting the apoptosis of VSMC (vascular smooth muscle cell) induced by TNF-α/act D.

Methods: Human aortic smooth muscle cell (HA-VSMC) was transfected with pcDNA3.1-cathepsin B and pSilencer2.

Very early stage detection of acute myocardial infarction by harmonic ultrasonic integrated backscatter.

To study the very early diagnosis of acute myocardial infarction (AMI) by harmonic imaging ultrasonic integrated backscatter (IBS). Thirty normal persons, 68 cases with AMI, of whom 28 cases were at the very early stage of acute myocardial infarction (in 2 h), and 40 cases with acute myocardial infarction (in 2 to 12 h) were examined by IBS and the cyclic variation of integrated backscatter (CVIB) with HP-5500 ultrasonic system in different segment (the segment of myocardial infarction and no myocardial infarction). In the segment of AMI of the very early stage (in 2 h) the IBS (dB) is much higher than that of the segment of no AMI (18.

[Study on the association of ABCA1 gene common variants with the risk of coronary atherosclerotic heart disease].

Objective: To investigate the association of R219K and M883I polymorphisms of ATP binding cassette transporter 1 gene with lipid metabolism and the susceptibility to coronary atherosclerotic heart disease in Chinese population.

Methods: Genotypes were determined by PCR-restriction fragment length polymorphism and Primer introduced restriction analysis-PCR techniques, respectively, in 248 unrelated CHD-free controls and 224 CHD cases.

Results: Smoking, high blood pressure and high serum glucose were independent risk factors for CHD.