Arthroscopic release combined with single-row fixation or double-row suture bridge fixation in patients with traumatic supraspinatus tear and adhesive capsulitis non-responsive to conservative management: A prospective randomized trial.

Background: There are few previous studies on traumatic supraspinatus tear with adhesive capsulitis. This study used arthroscopic release with single-row fixation or double-row suture bridge fixation to treat adhesive capsulitis of the shoulder with rotator cuff tears. Further, the clinical efficacy of arthroscopic release with single-row fixation and double-row suture bridge fixation was compared.

Computational methods for the prediction of chromatin interaction and organization using sequence and epigenomic profiles.

The exploration of three-dimensional chromatin interaction and organization provides insight into mechanisms underlying gene regulation, cell differentiation and disease development. Advances in chromosome conformation capture technologies, such as high-throughput chromosome conformation capture (Hi-C) and chromatin interaction analysis by paired-end tag (ChIA-PET), have enabled the exploration of chromatin interaction and organization. However, high-resolution Hi-C and ChIA-PET data are only available for a limited number of cell lines, and their acquisition is costly, time consuming, laborious and affected by theoretical limitations.

Ultrasensitive simultaneous voltammetric determination of 4-aminophenol and acetaminophen based on bimetallic MOF-derived nitrogen-doped carbon coated CoNi alloy.

Simultaneous electrochemical determination of 4-aminophenol (4-AP) and acetaminophen (ACOP) is crucial due to their high toxicity when are overused. Herein, a novel electrocatalyst of nitrogen-doped carbon coated CoNi alloy (CoNi@CN) is derived from bimetallic CoNi(BDC)(DABCO) for the first time. A series of characterizations demonstrate that composite has been successfully synthesized, and all elements are evenly distributed in the catalyst.

Differentiating between bipolar and unipolar depression using prefrontal activation patterns: Promising results from functional near infrared spectroscopy (fNIRS) findings.

Background: Bipolar depression (BD) is a unique, severe and prevalent mental illness that shares many similarities in symptoms with unipolar depression (UD). Improving precision of their diagnoses would enhance treatment outcome and prognosis for both conditions. This study aims to provide evidence from functional Near-Infrared Spectroscopy (fNIRS) as a potential tool to differentiate UD and BD based on their differences in hemodynamic change in the prefrontal cortex during verbal fluency tasks (VFT).

A Safe and Effective Posterior Intra-Articular Distraction Technique to Treat Congenital Atlantoaxial Dislocation Associated With Basilar Invagination: Case Series and Technical Nuances.

Background: The management of atlantoaxial dislocation (AAD) associated with basilar invagination (BI) is challenging, and traditional posterior-only approaches lack the ability to release the anterior soft tissue resulting in unsatisfactory reduction. Furthermore, vertebral artery anomalies and deformed anatomy increase surgical risks.

Objective: To introduce a safe and efficient technique to reduce congenital AAD and BI through a single-stage posterior-only approach.

Theoretical Study of Ozonation of Methylparaben and Ethylparaben in Aqueous Solution.

Parabens are widely employed in toothpaste, cosmetics, textiles, beverages, and preservatives, causing a serious environmental concern because they are endocrine-disrupting compounds (EDCs). As one of the highly reactive oxidants, ozone has a great effect on EDC removal. To understand the degradation and transformation of parabens in the aquatic environment and their toxicity to aquatic organisms, the degradation reaction of parabens initiated by O was studied meticulously using quantum chemical calculations.

Full insights into the roles of pH on hydroxylation of aromatic acids/bases and toxicity evaluation.

Advanced oxidation processes (AOPs) based on hydroxyl radicals (•OH) are the most important technologies for the removal of bio-recalcitrant organic pollutants in industrial wastewater. The pH is one of the crucial environmental parameters that affect the removal efficiency of pollutants in AOPs. In this work, the mechanistic and kinetic insights into the roles of pH on the hydroxylation of five aromatic acids and bases in UV/HO process have been investigated using theoretical calculation methods.

Thermal Ablation of Benign Thyroid Nodules and Papillary Thyroid Microcarcinoma.

Due to the increasing rates of physical examination and application of advanced ultrasound machines, incidences of benign thyroid nodules (BTNs) and papillary thyroid microcarcinoma (PTMC) were dramatically up-regulated in recent years. Thermal ablation (TA) has been widely used and regarded as a safe and effective method to eliminate or reduce BTNs and recurrent low-risk PTMC. However, conclusions using TA to treat primary PTMC are controversial.

[Inventory and Distribution Characteristics of China's Thermal Power Emissions Under Ultra-Low Reconstruction].

This study updates a bottom-up high-resolution emission inventory and estimates the concentrations, emission factors, emissions, and performance values of China's power plants, based on the data from continuous emission monitoring systems and environmental statistics in 2018. The results show that the ultra-low emission policy has significant effects: the average concentrations of SO, NO, and PM in thermal power plants were 37.57, 56.

[Contribution of Emissions from Cement to Air Quality in China].

This study analyzed the concentrations of exhaust gas in the process (kiln head and kiln tail) of China's cement industry, based on data from continuous emission monitoring systems network in 2018. The cement emission inventory for China with high resolution (high resolution cement emission inventory for China, HCEC), using the bottom-up approach, was established. The results indicated that during 2018, the total emissions of PM, SO, and NO were 72893, 92568, and 878394 t, respectively.

PIMD: An Integrative Approach for Drug Repositioning Using Multiple Characterization Fusion.

The accumulation of various types of drug informatics data and computational approaches for drug repositioning can accelerate pharmaceutical research and development. However, the integration of multi-dimensional drug data for precision repositioning remains a pressing challenge. Here, we propose a systematic framework named PIMD to predict drug therapeutic properties by integrating multi-dimensional data for drug repositioning.

Genomic analyses reveal evolutionary and geologic context for the plateau fungus .

Background: , which is only naturally found in the high-elevation extreme environment of the Tibetan Plateau, has been used in traditional Chinese medicine. Information concerning the evolutionary and geologic context of remains limited, however.

Methods: We constructed the high-quality genome of and provided insight into the evolution and ecology of using comparative genomics.

Quantitative Reduction of Basilar Invagination With Atlantoaxial Dislocation by a Posterior Approach.

Objective: This study evaluated the feasibility and efficacy of quantitative reduction and fixation to treat basilar invagination (BI) with atlantoaxial dislocation (AAD).

Methods: Posterior occipitocervical angle (POCA), occiput-C2 angle (Oc-C2A), clivusaxial angle (CAA), and C2-7 angle (C2-7A) were considered for quantitative reduction. Twelve patients with BI complicated with AAD received posterior interarticular release and individualized cage implantation to restore vertical dislocation.

Air pollution emissions from Chinese power plants based on the continuous emission monitoring systems network.

To meet the growing electricity demand, China's power generation sector has become an increasingly large source of air pollutants. Specific control policymaking needs an inventory reflecting the overall, heterogeneous, time-varying features of power plant emissions. Due to the lack of comprehensive real measurements, existing inventories rely on average emission factors that suffer from many assumptions and high uncertainty.

Spatial density of open chromatin: an effective metric for the functional characterization of topologically associated domains.

Topologically associated domains (TADs) are spatial and functional units of metazoan chromatin structure. Interpretation of the interplay between regulatory factors and chromatin structure within TADs is crucial to understand the spatial and temporal regulation of gene expression. However, a computational metric for the sensitive characterization of TAD regulatory landscape is lacking.

The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3',5'-monophosphate (Epac) for central nervous system trauma.

Millions of people worldwide are affected by traumatic spinal cord injury, which usually results in permanent sensorimotor disability. Damage to the spinal cord leads to a series of detrimental events including ischaemia, haemorrhage and neuroinflammation, which over time result in further neural tissue loss. Eventually, at chronic stages of traumatic spinal cord injury, the formation of a glial scar, cystic cavitation and the presence of numerous inhibitory molecules act as physical and chemical barriers to axonal regrowth.

Anisotropic ultrasensitive PdTe-based phototransistor for room-temperature long-wavelength detection.

Emergent topological Dirac semimetals afford fresh pathways for optoelectronics, although device implementation has been elusive to date. Specifically, palladium ditelluride (PdTe) combines the capabilities provided by its peculiar band structure, with topologically protected electronic states, with advantages related to the occurrence of high-mobility charge carriers and ambient stability. Here, we demonstrate large photogalvanic effects with high anisotropy at terahertz frequency in PdTe-based devices.

Exosome-transferred LINC01559 promotes the progression of gastric cancer via PI3K/AKT signaling pathway.

Increasing evidence indicates that long non-coding RNAs (lncRNAs) are associated with the progression of human cancers. However, the expression level and function of LINC01559 (long intergenic non-protein coding RNA 1559) in gastric cancer (GC) are rarely reported. Here we found that LINC01559 was upregulated in GC tissues based on GEPIA (Gene Expression Profiling Interactive Analysis) and TCGA (The Cancer Genome Atlas) databases.

Exploring the classification of cancer cell lines from multiple omic views.

Background: Cancer classification is of great importance to understanding its pathogenesis, making diagnosis and developing treatment. The accumulation of extensive omics data of abundant cancer cell line provide basis for large scale classification of cancer with low cost. However, the reliability of cell lines as in vitro models of cancer has been controversial.

Correction to: CRISPR-Cas9 mediated targeted disruption of FAD2-2 microsomal omega-6 desaturase in soybean (Glycine max.L).

An amendment to this paper has been published and can be accessed via the original article.

MOF-818 metal-organic framework-reduced graphene oxide/multiwalled carbon nanotubes composite for electrochemical sensitive detection of phenolic acids.

Herein, a novel bimetallic MOF-818@reduced graphene oxide/multiwalled carbon nanotubes (RGO/MWCNTs) composite was successfully synthesized by a facile solvothermal method. Characterized by scanning electron microscopy, X-ray diffraction, N adsorption-desorption isotherm, X-ray photoelectron spectroscopy and electrochemical measurements, MOF-818@RGO/MWCNTs composite possesses hierarchical porous structures, good electrical conductivity and abundant active sites. The MOF-818@RGO/MWCNTs/GCE exhibits excellent electrocatalytic activity to phenolic acid compounds: caffeic acid (CA), chlorogenic acid (CGA) and gallic acid (GA).

Protective effect of hypothermia and vitamin E on spermatogenic function after reduction of testicular torsion in rats.

This study was designed to investigate the protective effect of hypothermia and vitamin E on spermatogenic function after reduction of testicular torsion in rats. Ninety-six pure inbred male SD rats were divided into group A, B, C and D according to the principle of body weight and birth similarity, with 24 rats in each group. Four groups of rats were respectively twisted on the left testis to establish unilateral testicular torsion rats.

[Contribution of Emissions from the Iron and Steel Industry to Air Quality in China].

Based on the data from a continuous emission monitoring systems network in 2015, this study analyzed the compliance rates of exhaust gas in the processes of China's iron and steel industry, and established a high-resolution steel plant emission inventory for China (HSEC, 2015), based on the bottom-up method. The contribution of emissions from the iron and steel industry to regional air quality was quantitatively simulated using a CAMx model. The results showed that in 2015, the total emissions of SO, NO, PM, PM, PCDD/Fs, VOCs, CO, BC, OC, EC, and F were 374800 t, 720500 t, 334800 t, 150300 t, 1.