HM-chromanone attenuates obesity and adipose tissue inflammation by downregulating SREBP-1c and NF-κb pathway in high-fat diet-fed mice.

Obese adipose tissue produces various pro-inflammatory cytokines that are major contributors to adipose tissue inflammation. The present study aimed to determine the effects of HM-chromanone (HMC) against obesity and adipose tissue inflammation in high-fat diet-fed mice. Twenty-four C57BL/6J male mice were divided into three groups: ND (normal diet), HFD (high-fat diet), and HFD + HMC.

Analysis of public perception of national obesity management policy.

Purpose: This study aimed to provide essential data necessary for shaping future obesity policy directions and strengthening the effectiveness of such measures.

Methods: A literature review and expert meetings were conducted to identify policy objectives that should be included in the comprehensive national obesity management plan. Based on these objectives, a questionnaire was developed, and a survey was conducted nationwide through an online panel targeting citizens aged 15-69.