Publications by authors named "Bo Kyu Choi"

Article Synopsis
  • Delirium occurs in up to 50% of patients after high-risk surgeries and can negatively impact long-term health outcomes; the study aimed to use machine learning to predict this condition using sleep data from polysomnography (PSG) and questionnaires.
  • Researchers analyzed data from 912 adults who had surgeries under general anesthesia, identifying key risk factors for delirium such as medication use, surgery duration, and sleep issues like REM episodes and daytime sleepiness.
  • The machine learning model showed strong predictive capabilities, achieving an AUC of 0.84 when combining clinical and PSG data, emphasizing the importance of sleep-related factors in identifying patients at risk for delirium post-surgery.
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Juvenile myoclonic epilepsy (JME) is a common adolescent epilepsy characterized by myoclonic, generalized tonic-clonic, and sometimes absence seizures. Prognosis varies, with many patients experiencing relapse despite pharmacological treatment. Recent advances in imaging and artificial intelligence suggest that combining microstructural brain changes with traditional clinical variables can enhance potential prognostic biomarkers identification.

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Sepsis is a dysregulated immune response to infection that leads to organ dysfunction and is associated with a high incidence and mortality rate. The lack of reliable biomarkers for diagnosing and prognosis of sepsis is a major challenge in its management. We aimed to investigate the potential of three-dimensional label-free CD8 + T cell morphology as a biomarker for sepsis.

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Article Synopsis
  • Early diagnosis and treatment of meningitis and encephalitis are critical, prompting a study to create and test an AI model for determining the causes of these conditions.
  • The study involved analyzing data from 283 patients to develop the AI model and validating it with 220 additional patients, focusing on four potential causes: autoimmunity, bacteria, virus, and tuberculosis.
  • The AI model significantly outperformed human clinicians in identifying the causes of meningitis and encephalitis, achieving high accuracy metrics, which underscores its potential for improving patient outcomes in these severe conditions.*
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Background: Ischemic stroke with active cancer is thought to have a unique mechanism compared to conventional stroke etiologies. There is no gold standard guideline for secondary prevention in patients with cancer-related stroke, hence, adequate type of antithrombotic agent for treatment is controversial.

Methods: Subjects who were enrolled in National Health Insurance System Customized Research data during the period between 2010 and 2015 were observed until 2019.

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Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that mainly affects young adults with known risk factors of prothrombotic conditions, pregnancy, infection, malignancy, and drugs. Dutasteride is a 5α-reductase inhibitor that is used for benign prostate hypertrophy and androgenetic alopecia. To date, CVT caused by dutasteride use has not been reported.

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