Experimental study of growth kinetics of CO hydrates and multiphase flow properties of slurries in high pressure flow systems.

The formation and accumulation of hydrates in high pressure oil and gas pipelines bring great risks to field development and deep-water transportation. In this paper, a high pressure flow loop equipped with visual window was used to study the growth process of hydrates in a pipe flow system and slurry flow characteristics. Deionized water, industrial white oil and CO were selected as the experiment medium.

Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips.

To understand how differentially methylated genes (DMGs) might affect the pathogenesis of Kashin-Beck disease (KBD). Genome-wide methylation profiling of whole blood from 12 matched KBD and controls pairs was performed using a high-resolution Infinium 450 K methylation array. In total, 97 CpG sites were differentially methylated in KBD compared to the normal controls; of these sites, 36 sites were significantly hypermethylated (covering 22 genes) and 61 sites were significantly hypomethylated (covering 34 genes).