Novel functional hydrogels based on lignin‑silver nanoparticles with adhesion, antimicrobial, antioxidant and anti-freezing properties for wound dressings and pressure strain sensors.

As wound dressings and wearable electronics advance, it is critical to develop an efficacious strategy for integrating a variety of powerful functions into hydrogels. In this work, sodium lignosulfonate‑silver nanoparticles and the functional [2-(methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide structure (SBMA) are introduced into the multifunctional lignin-based hydrogel system. The sodium lignosulfonate‑silver nanoparticles, by catalyzing multiple redox reactions, facilitate the swift curing of hydrogels at room temperature.

Generating a 30 m Hourly Land Surface Temperatures Based on Spatial Fusion Model and Machine Learning Algorithm.

Land surface temperature (LST) is a critical parameter for understanding climate change and maintaining hydrological balance across local and global scales. However, existing satellite LST products face trade-offs between spatial and temporal resolutions, making it challenging to provide all-weather LST with high spatiotemporal resolution. In this study, focusing on Chengdu city, a framework combining a spatiotemporal fusion model and machine learning algorithm was proposed and applied to retrieve hourly high spatial resolution LST data from Chinese geostationary weather satellite data and multi-scale polar-orbiting satellite observations.

Timing of Iliofemoral Vein Stent Implantation after Mechanical Thrombectomy for Acute Iliofemoral Venous Thrombosis.

Objectives: Comparison of the treatment effects of immediate stent implantation vs staged stent implantation after AngioJet mechanical thrombectomy in patients with acute iliofemoral venous thrombosis.

Methods: A study included 80 patients with acute iliofemoral venous thrombosis formed between June 2021 and February 2023. They were divided into two groups: the direct implantation group (37 patients, 9 males) and the staged implantation group (43 patients, 10 males).

Clinical Symptoms of Postburn Hypertrophic Scars and Analysis of Risk Factors for Itching and Pain Requiring Pharmacological Intervention.

Background: Pruritus and pain symptoms secondary to hypertrophic scars (HTSs) are associated with multiple factors, with age, body mass index (BMI), and scar thickness being the main risk factors (RFs).

Objective: This study mainly discusses the clinical symptoms associated with postburn HTSs and analyzes RFs for itching and pain requiring pharmacological intervention.

Materials And Methods: All clinical data of 93 patients with postburn HTSs who visited the Burn Department of Shanghai Seventh People's Hospital between January 1, 2021 and January 1, 2023 were collected and analyzed retrospectively.

Multi-indicator assessment of heavy metal pollution in Qinzhou Harbour sediments: Unraveling ecological and human health risks.

The study of heavy metal content in the sediments of the coastal zone of Qinzhou Harbour was used to analyse the level, distribution and sources of heavy metal pollution in the region and its hazards to the ecological environment and human health. The results showed that the average concentrations of Mn, Ni, Cr, Cu, and Pb exceeded background values along the shores of Qinzhou Harbour, Guangxi. Comprehensive assessments using Igeo, RI, and PLI identified Cu, Ni, and Pb as primary contaminants in the area, presenting slight to moderate ecological risks and biological toxic effects.

Diagnostic Value of Cerebrospinal Fluid Sequencing for Neurosyphilis with Cognitive Impairment.

Neurosyphilis (NS) is an infectious disease caused by invading the central nervous system. It can manifest at any stage of syphilis, and is often misdiagnosed due to its atypical and progressive symptoms. The increasing incidence of NS underscores the necessity for early and accurate diagnosis.

Efficacy and safety of nine immunosuppressive agents for primary focal segmental glomerulosclerosis in adults: a pairwise and network meta-analysis.

Background: Immunosuppressants are widely used as the preferred treatment for primary focal segmental glomerulosclerosis (pFSGS). Nevertheless, controversies persist regarding the effectiveness and side effects of different immunosuppressive medications.

Methods: From July 2023 until June 2024, we systematically searched PubMed, Cochrane Library, Web of Science, clinicalrials.

Ultrahard and Ultraflexible Supramolecular Hydrogel with Superenergy Dissipating Structure for Biomimetic Skin.

How to integrate the "soft" (flexibility and self-healing properties) and "hard" (shape retention) into the supramolecular hydrogel system is an attractive challenge. In this work, a supramolecular hydrogel with an energy dissipation structure is designed and prepared for intelligent biomimetic skin. Lignin molecules with disulfide bonds of fracture and healing activities are introduced into the hydrogel system through covalent bonds.

The Molecular Mechanism Investigation of HBP-A Slows Down Meniscus Hypertrophy and Mineralisation by the Damage Mechanical Model.

HBP-A is the main active component of a traditional Chinese medicine Huaizhen Yanggan Capsule, for the remarkable treatment of knee osteoarthritis (KOA). This study aimed to elucidate the ameliorative effect of HBP-A on meniscus hypertrophy and mineralisation in KOA and the molecular mechanism of its action. An Hartley guinea pig model of KOA that underwent anterior cruciate ligament transection (ACLT) and a model of rat primary meniscus fibrochondrocytes (PMFs) were used to investigate the ameliorative effect of HBP-A on meniscal hypertrophy and calcification and its signal transduction mechanism of action.

A retrospective single cohort study on the 5-13 year clinical outcomes of implant-supported cross-arch fixed dental prostheses with monolithic zirconia-based frameworks.

Purpose: To investigate the mid-to-long term clinical outcomes of the implant-supported cross-arch fixed dental prostheses (IFCDPs) with monolithic zirconia-based frameworks and related risk factors of success and survival.

Materials And Methods: This retrospective study encompassed individuals exhibiting terminal dentition or edentulism in the maxilla and/or mandible who underwent treatment involving IFCDPs with monolithic zirconia frameworks. Inclusion criteria required a documented follow-up period of at least five years post-definitive prosthesis delivery.

A 3D mixed ion-electron conducting framework for dendrite-free lithium metal anodes.

To enable the practical application of lithium metal batteries, it is crucial to address the challenges of dendrite growth and volume expansion in lithium metal anodes. A 3D framework offers an effective solution to regulate the lithium plating/stripping process. In this work, we present a 3D mixed ion-electron conducting (MIEC) framework as a lithium metal anode, achieved by conformally coating carbon nanotubes (CNTs) onto LiLaTiO (LLTO) particles.

Co-pyrolysis of corn stalk and high-density polyethylene with emphasis on the fibrous tissue difference on thermal behavior and kinetics.

The thermal properties of various corn stalk tissues (including stem, husk, ear, cob, and leaf), high-density polyethylene (HDPE), and their blends were investigated using thermogravimetric analysis under a nitrogen atmosphere. The results indicate that the thermal decomposition process of corn stalk tissue/HDPE mixtures is delayed with an increasing heating rate, regardless of the tissue type. Besides, the structural differences among various corn stalk tissues significantly influence their thermal behavior, product distribution, and co-pyrolysis kinetics with HDPE.

A meta-analysis of randomized controlled trials examining the efficacy and safety of elemene in combination with chemotherapy for the treatment of gastric cancer.

Background: Elemene is a naturally occurring chemical derived from plants of the Zingiberaceae family, and it finds application in several cancer-related contexts. Nevertheless, there is a dearth of comprehensive assessment about the combined effectiveness and safety of chemotherapy in gastric cancer (GC).

Objective: To investigate the safety and effectiveness of elemene in conjunction with chemotherapy for the treatment of Gastric cancer.

Extraction, purification, structural characterization, bioactivities, modifications and structure-activity relationship of polysaccharides from : a review.

(Thunb.) Ker Gawl., is a traditional Chinese medicine (TCM) with a history of thousands of years.