[Caries preventive effect of toothpastes with detonation nanodiamonds on the dental enamel of rats].

The aim of the study was to evaluate the abrasive effect of toothpaste with nanodiamonds of detonation synthesis of different concentrations on tooth enamel of experimental animals (rats). The analysis of microphotographs obtained by scanning electron microscopy from all studied groups showed different abrasive and polishing effects of nanodiamonds in all observed anatomical zones on the vestibular surface of rat tooth enamel. At all concentrations of pastes containing nanodiamonds, tightly attached nanodiamonds were observed on the vestibular surface of the enamel of the teeth under study, there was a tendency to the formation of depots.

[Morphological study of histiocytosis from Langerhans cells in jaw bones].

Histiocytosis of the jaws in biopsies from 17 patients aged 19 to 51 years were studied at light and electron microscopy level. Birbek's bodies were found in Langerhans cells in all the biopsies confirming the diagnosis of Langerhans cell histiocytoma. The structure of Birbek's bodies changed depending on the treatment--radiation or chemotherapy.

[Morphologic studies of bronchial biopsies in chronic bronchitis before and after treatment].

Bronchial biopsies in patients with chronic bronchitis were studied histochemically, light and electron microscopically before and after conventional treatment and combined therapy (standard regimen plus He-Ne laser puncture). The conclusion is made that the combined therapy is more effective especially at early stages of the disease when irreversible sclerotic changes in the submucosa and microcirculatory bed are absent. This therapy at early stages of the disease stimulates regeneration of the surface bronchial epithelium and facilitates reversibility of initial metaplasia.

[Genetic control of the number of copies of type K2 killer plasmids in Saccharomyces cerevisiae].

13 non-linked chromosomal mutations derepress the negative genetic control of copy number of K2 yeast killer plasmids and lead to 1.5-2-fold elevating of copy number of that type plasmids -L2A and M2 virus-like dsRNA. The content of both plasmids is increased 3-5-fold in cells with chromosomal ski5 mutation, as compared to the strains of wild type.

[Experimental candidiasis of the mouth mucosa under conditions of the inhibition of leukopoiesis].

In the experiments on rats (25--experimental rats, 15--the control group) using histological and electron microscopic methods the authors studied the nature of inflammatory response in the mouth cavity mucosa. Inflammatory response had an acellular nature with the predominance of alternative processes.

[Changes in the respiratory organs in experimental adenovirus infection].

An experiment on 6 green monkeys and on 286 cotton newly born rats was made with the aim of studying the lung during experimental adenovirus infection. All the animals during different terms of infection (from 6 hours and up to 40 days) have been studied. Several morphological changes were discovered in the lungs of monkeys and rats after 6 hours of infection and were retained up to the 10-th day of infection.

[Variants of the ultrastructure of bronchial ciliary cells].

The structure of the ciliated epithelium and its regeneration under normal conditions were studied using biopsy specimens of the trachea and extrapulmonary bronchi from healthy dogs. The specimens were processed with the routine methods for electron microscopy. Along with the typical structure of the ciliated cells there were observed various deviations considered earlier as consequences of bronchopulmonary pathology: changed cytoplasm of the ciliated cells in the form of cytoplasmic processes or follicles.

[Characteristics of development of the rat embryonal lung after resection of the maternal lung].

Histological and electron microscopic studies of embryos from pulmonectomized female rats have revealed retarded differentiation of respiratory rudiment epithelium manifested in delayed appearance of osmiophylic laminar corpuscles and decreased number of type II pneumocytes in respiratory rudiment lining. Osmiophylic laminar corpuscles in them were less differentiated, as compared to the control. In addition, embryonic lungs in pulmonectomized rats were characterized by excessive mesenchyma development and respective decrease in respiratory rudiment area.

[Structural changes in the lungs induced by different levels of hyperbaric oxygenation].

Morphological and ultrastructural changes in the lungs of 30 rabbits placed into the altitude chamber with 100% O2 and the pressure of 2, 2.5, 3 and 4 ata for 60 min daily during 1, 2 and 3 weeks have been studied. Morphological changes in the lungs were shown to depend on the degree and duration of oxygen pressure.

[Mechanism and time periods of the development of hyaline membranes in acute respiratory failure of traumatic origin].

The model of chest trauma accompanied by acute respiratory failure was studied on 78 guinea-pigs. Histological and electron microscopic methods have revealed a typical pattern of shock lung: combination of diffuse bilateral microfocal distelectases and microcirculation disturbances, i.e.

[Morphological and ultrastructural changes in the lungs as affected by different shock-producing factors].

Experiments on 234 guinea-pigs were made to study the effects of 3 shock-inducing agents (acute hemorrhage, graded chest injury, Salmonella endotoxin). Application of histological methods, electron microscopy, electron histochemistry with the use of rutenium red and Pattle 's method for determining the stability of pulmonary vesicles disclosed that the typical reaction seen within the first 6 hours was the spasm of bronchioles and venules, followed by the development of bilateral small-focal contractile atelectases and microcirculatory disorders in the form of the sludge syndrome, leukostasis, accumulation of megakaryocytes, DVS , and dystrophy of the capillary endothelium. Following 12-24 hours structural changes in the surfactant system supervened: the loss of lamillar bodies by large alveolocytes, disorganization of the surfactant film, a critical fall of the Pattle stability.