Functional Mechanical Behavior and Biocompatible Characteristics of Graphene-Coated Cardiovascular Stents.

Percutaneous Coronary Intervention (PCI) is a treatment method that involves reopening narrowed arteries with a balloon catheter that delivers a cylindrical, mesh-shaped implant device to the site of the stenosis. Currently, by applying a coating to a bare metal stent (BMS) surface to improve biocompatibility, the main risks after PCI, such as restenosis and thrombosis, are reduced while maintaining the basic requirements for the mechanical behavior of the stent itself. In this work, for the first time, the development and optimization process of the spatial structure of the Co-Cr stent (L-605) with a graphene-based coating using cold-wall chemical vapor deposition (CW-CVD) to ensure uniform coverage of the implant was attempted.

Composite Nanostructures for the Production of White Light.

In this work, two different composite nanostructures, YAG:Ce and GaInN, were prepared by the Urea Glass Route method and tested for the production of white light. The first composite was prepared by synthetizing the GaInN nanoparticles in the presence of YAG:Ce nanoparticles. The second one was prepared by synthetizing YAG:Ce nanoparticles in the presence of GaInN nanoparticles.

Urea Glass Route as a Way to Optimize YAGG:Ce,Cr,Pr Nanocrystals for Persistent Luminescence Applications.

A new approach for the synthesis of YAlGaO (YAGG) nanophosphors allowing the preparation of crystallites with sizes starting from 45 nm is presented. The controllability of the energy and trap density of the resulting material samples by annealing temperature was confirmed by thermoluminescence (TL) measurements. It has been shown that the annealing of samples at temperatures up to 1300 °C does not cause any substantial growth of crystallites, still remaining below 100 nm, but leads to changes in the activation energy of the persistent luminescence (PersL) process.

Influence of long-term intensive use of irrigated meadow-chernozem soil on the biological activity and productivity of the arable layer.

The research was carried out on the territory of the Russian Federation in the forest-steppe region of the south Western Siberia (Omsk state), in the long-term (43 years) stationary experiment. Sprinkling was used for irrigation in the experiment. The number of different physiological groups of microorganisms, the cellulolytic activity of the soil, and nitrification capacity were determined under the sowing of an eight-field grain-grass crop rotation (perennial grasses (Bunias orientalis L.

Size-Dependent Persistent Luminescence of YAGG:Cr Nanophosphors.

In the current work, YAGG:Cr nanophosphors were synthesized by the Pechini method and then annealed at different temperatures in the range 800-1300 °C. The structure and morphology of the samples were characterized by X-ray Powder Diffraction (XRPD). The lattice parameters and average crystalline sizes as site occupation by Al and Ga ions were calculated from the Rietveld refinement data.

Effect of Graphene Addition on the Thermal and Persistent Luminescence Properties of GdCeGaAlO and GdCeDyGaAlO Ceramics.

The gadolinium, gallium, aluminum garnet doped with cerium and co-doped with dysprosium ions were prepared using sol gel method. The SEM images show that after synthesis, the grains are below 100 nm. The powders were ultrasonically mixed with graphene nanoflakes and ceramics were prepared using the high pressure low temperature sintering technique.

SIMULTANEOUS HIATAL HERNIA PLASTICS WITH FUNDOPLICATION, LAPAROSCOPIC CHOLECYSTECTOMY AND UMBILICAL HERNIA REPAIR.

The article presents a case report of patients with multimorbid pathology - hiatal hernia with gastroesophageal reflux disease, cholecystolithiasis and umbilical hernia. Simultaneous surgery was performed in all cases - laparoscopic hiatal hernia with fundoplication, laparoscopic cholecystectomy and umbilical hernia alloplasty (in three cases - by IPOM (intraperitoneal onlay mesh) method and in one - hybrid alloplasty - open access with laparoscopic imaging). After the operation in one case there was an infiltrate of the trocar wound, in one case - hyperthermia, which were eliminated by conservative methods.

SIMULTANEOUS OPERATIONS DURING UMBILICAL AND PARAUMBILICAL HERNIA REPAIR: POSSIBLE OR NECESSARY?

Objective: The aim of the study was to determine the possibility and effectiveness of simultaneous surgical interventions in umbilical and paraumbilical hernia repair.

Patients And Methods: Material and methods: 148 case histories were analyzed concerning patients who were routinely admitted to the surgical department of the Kharkiv Regional Council's Municipal Non-Profit Enterprise «Regional Clinical Hospital» between 2017 and 2019, and who underwent umbilical and paraumbilical hernia repair simultaneously with operations related to some other surgical pathology (group 1, n = 67) or in separate interventions (group 2, n = 81). All patients were routinely operated after a set of mandatory and additional general clinical, laboratory and instrumental research conducted in accordance with the existing guidelines.

Graphene Coating Obtained in a Cold-Wall CVD Process on the Co-Cr Alloy (L-605) for Medical Applications.

Graphene coating on the cobalt-chromium alloy was optimized and successfully carried out by a cold-wall chemical vapor deposition (CW-CVD) method. A uniform layer of graphene for a large area of the Co-Cr alloy (discs of 10 mm diameter) was confirmed by Raman mapping coated area and analyzing specific G and 2D bands; in particular, the intensity ratio and the number of layers were calculated. The effect of the CW-CVD process on the microstructure and the morphology of the Co-Cr surface was investigated by scanning X-ray photoelectron microscope (SPEM), atomic force microscopy (AFM), scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS).

Particle size-related limitations of persistent phosphors based on the doped YAlGaO system.

Co-doped Ce, Cr and Pr yttrium-aluminium-gallium garnet powders of various sizes were obtained by co-precipitation method. The microstructure and morphology were investigated by XRPD, TEM and gas porosimetry. The luminescence properties were studied by excitation and emission spectra, quantum yield and decay times.

THE VALUE OF DENTAL EXAMINATION FOR EARLY DIAGNOSIS OF THE MUSCULOSKELETAL SYSTEM DISEASES.

Objective: The aim: The purpose of the study was to determine the correspondence between the location of the tongue median line and the degree of distortion of the vertebral column at different levels in children with scoliosis.

Patients And Methods: Materials and methods: Totally 56 children (30 girls, 26 boys) aged 11-14 years were examined, with a duration of musculoskeletal disorders 1-3 years. For each participant an oral cavity examination was performed, the position of the middle line of the tongue was determined.

Phospholipid distribution in the cytoplasmic membrane of Gram-negative bacteria is highly asymmetric, dynamic, and cell shape-dependent.

The distribution of phospholipids across the inner membrane (IM) of Gram-negative bacteria is unknown. We demonstrate that the IMs of and are asymmetric, with a 75%/25% (cytoplasmic/periplasmic leaflet) distribution of phosphatidylethanolamine (PE) in rod-shaped cells and an opposite distribution in filamentous cells. In initially filamentous PE-lacking cells, nascent PE appears first in the periplasmic leaflet.

Estimation to efficiency of the multifunction method оf endometriosis ovariеs treatment.

Objective: The aim: The aim of the study was to improve the results of treatment of patients with endometriosis by using a combination method of therapy.

Patients And Methods: Materials and methods: For two years, 136 women of reproductive age who underwent laparoscopic surgeries for ovarian endometriosis were monitored: Group I (n = 24) did not receive any hormonal treatment in the perioperative period; Group II (n = 32) - received gonadotropin-releasing hormone agonists within 3 months after surgery; Group III (n = 80) prior to laparoscopic removal of the ovarian cyst used gonadotropin-releasing hormone agonists - Triptorelin 3.75 mg intramuscularly for 2 months, as well as three months after surgery.

Methods of preventive intervention in women with multiple pregnancies in non-assymptomic circulation.

Objective: The aim: The purpose of the study is a comparative evaluating the effectiveness of using the different methods of treatment of miscarriage in multiple pregnancies taking into account the condition of the cervix.

Patients And Methods: Materials and methods: 86 pregnant women with diarrheal twins were monitored. On the basis of studying the premorbid background, somatic and reproductive history, features of the gestational period, leading antenatal risk factors for the development of complications in multiple pregnancies were identified.

Basic clinical and pathogenetic aspects of developing the complications during multiple pregnancies.

Objective: Introduction: In order to evaluate the value of the Placenta Growth Factor (PlGF) in the developing the gestational complications during multiple pregnancies, a study of this indicator in serum of 320 pregnant women with multiple pregnancies in the first trimester, as well as 40 pregnant women with single pregnancy, constituted a control group. The aim: of the study is to investigate the effect of the placental growth factors on gestational process during multiple pregnancies.

Patients And Methods: Materials and methods: A prospective study of maternity pregnancy in 320 females with multiple pregnancies was conducted, which comprised the main group of the subjects and 40 healthy women with unipolar pregnancy.

The problem of miscarriage in multiple pregnancy.

Objective: Introduction: We present the results of the combined method of treatment and prevention of miscarriage in women with a multiple pregnancy and a high risk of the threat of terminating the pregnancy because of using the obstetric unloading pessaries, combined with micronized progesterone. The efficiency of this method of treatment is evidenced by the rapid elimination of clinical symptoms of threatened abortion, accelerating the regression of ultrasound markers, reducing the number of complications in of pregnant women and reducing the time of their stay in hospital. The aim: To evaluate the effectiveness of the handling the obstetric pessary in combination with micronized progesterone at women with multiple pregnancies and a high risk of miscarriage.

Vibrational spectra of DNA in the confined interglobular volume of photonic crystal.

The impact of confinement of DNA molecules in a limited volume of the cavity of photonic crystals (PC) on the vibrational properties of the DNA molecule and its conformation is studied. According to our preliminary study, the aqueous shell is removed when the DNA molecules are infiltrated into the PC cavities. Raman scattering (RS) DNA marker lines showed a dramatic conformational change of DNA in the PC cavities and the appearance of new unknown conformational states.

Synthesis of an Enantiomerically Pure Inherently Chiral Calix[4]Arene Phosphonic Acid and Its Evaluation as an Organocatalyst.

A facile method for the preparation of enantiomerically pure inherently chiral calix[4]arene phosphonic acid (cR,pR)-7 in four steps starting from the readily available and previously synthesized (cS)-enantiomer of calix[4]arene acetic acid 1 or its methyl ester 2 was developed. The first tests of this unique calixarene Brönsted acid with inherent chirality in organocatalysis of the aza-Diels-Alder reaction of imines with Danishefsky's diene and epoxide ring opening by benzoic acid were performed. The calixarene phosphonic acid (cR,pR)-7 shows good catalytic activities but with low enantioselectivities in these reactions.

[Nonplatelet Effects of Ticagrelor].

This review summarizes current knowledge concerning "nonplatelet effects of P2Y12 receptor antagonist ticagrelor. We show the experimental and clinical evidence that ticagrelor increases plasma concentration of adenosine as a potential mechanism of additive effects of ticagrelor. In addition, we sought to compare the clinical profile of ticagrelor with pharmacological effects of adenosine and discuss from this point of view the effects of ticagrelor on vascular tone, cardiac electrophysiology, ischemia/reperfusion injury, immunity and inflammatory reactions, peripheral nerves.

Angular shaping of fluorescence from synthetic opal-based photonic crystal.

Spectral, angular, and temporal distributions of fluorescence as well as specular reflection were investigated for silica-based artificial opals. Periodic arrangement of nanosized silica globules in the opal causes a specific dip in the defect-related fluorescence spectra and a peak in the reflectance spectrum. The spectral position of the dip coincides with the photonic stop band.

[Evaluation of intestinal viability on a simulation model of a small ileus based on determination of dielectric parameters].

Interrelationship between dielectric parameters and level of ATPH before and during ischemia, as well as with indices of survival after elimination of strangulation, was estimated on a simulation model of strangulation ileus in rats. The data obtained permit to suppose, that parameter tg δm may be used as effective noninvasive criterion of diagnosis in real time for estimation of the intestinal wall state in strangulation. Resection of the infringed intestine without elimination of strangulation is necessary in tg δm less than 2.

[Tactics of "damage control" in the injured persons with severe combined trauma of abdominal organs].

In the clinic in 2000 - 2013 yrs of 42 injured persons with severe combined trauma of abdominal organs were treated, in 18 of them the method of a multi-staged treatment (damage control) with a short-term operative intervention on the first stage was applied, what permitted to lower postoperative lethality by 22.3%, and rate of purulent-septic complications--by 18.1%.

[Impact of abdominal cavity open EHF irradiation on activity of adhesive process in peritonitis].

In experiment on 45 rats a purulent peritonitis was simulated. There was established, that on background of a standard therapy for peritonitis application of abdominal cavity open irradiation of extreme high frequency (EHF) have promoted rapid stabilization of the lipid metabolism indices and the blood coagulation system, the reduction of intensity of lipids peroxidal oxidation processes and severity of systemic inflammatory reaction. Under the influence of complex treatment the severity of adhesive process was reduced in 5.

[Roentgen-surgical interventions in combined treatment of patients, suffering hepatic metastases of noncolorectal cancer].

Results of combined treatment, using roentgen-surgical interventions, of 58 patients, suffering noncolorectal metastatic affection of the liver, complicated in 20 (34.5%) of them by obturation jaundice, were analyzed. While resectability of the metastases, preoperatively chemotherapy (CHT) or chemoembolization of hepatic artery (CHEHA) in 1 - 2 courses were performed, and then - hepatic resection of various volume, adjuvant regional CHEHA or systemic CHT.