Publications by authors named "Blocker T"

. This study aimed to evaluate two real-time target tracking approaches for magnetic resonance imaging (MRI) guided radiotherapy (MRgRT) based on foundation artificial intelligence models..

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Villitis of unknown etiology (VUE) and chronic deciduitis with plasma cells (CD) are supposed to be non infectious placental lesions caused by a pathologic immune reaction similar to a host versus graft mechanism. In some investigations, infection of human trophoblastic cells with human papilloma virus (HPV) has been described, and a relationship with miscarriage, preeclampsia, and chronic inflammatory placental lesions has been suspected. Infection with enterovirus, especially Coxsackievirus, has been observed in cases with spontaneous abortion and adverse perinatal outcome, respectively.

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This study focused to investigate a possible association of extensive umbilical hypercoiling (displaying an umbilical coiling index [UCI] of at least 1.0 coils/cm), clinical outcome, and associated pathoanatomical placental lesions. Of the 771 singleton placentas from the second and third trimesters submitted for pathoanatomical evaluation, 15 cases (2%) displayed extensive hypercoiling.

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Dizygotic twin pregnancies with discordant manifestation of abnormalities with unclear etiology are of interest because they arise in the same environment. We present a dizygotic third trimester twin placenta with discordant villous maturation, one placenta lacking developed syncytiocapillary membranes. The twins were eutrophic with no perinatal or postnatal complications.

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Massive perivillous fibrin deposition (MFD) is a morphologically defined severe placental lesion associated with perinatal morbidity and mortality. The etiology is unknown, and recurrence risk in subsequent pregnancies is assumed to be high. In most cases, a pathologic immune reaction is supposed to be responsible for the lesion.

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Pair bonds are the cornerstone of a monogamous relationship. When individuals of the same species engage in monogamy and promiscuity (i.e.

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Objective: To compare the degree and duration of corneal anesthesia of a novel viscous ophthalmic lidocaine hydrochloride preparation vs. two commonly used ophthalmic anesthetic preparations.

Methods: Each subject was randomly selected to receive 2 of 4 treatments at 2 different time periods separated by a 1 week washout: 3.

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Social recognition is an integral component of behavior that underlies many much larger behavioral suites. For example, monogamous pair bonding is relatively meaningless if an individual cannot recall with whom the bond was with. Prairie voles () are a socially monogamous rodent, well known for their long-term pair bonds between males and females.

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Massive perivillous fibrin deposition (MFD) is a placental lesion of unknown etiology associated with perinatal morbidity and mortality and recurrence risk in subsequent pregnancies. We report a 34 weeks' gestation dizygotic twin pregnancy with discordancy for MFD and for intrauterine growth restriction after in vitro fertilization (IVF). Only the smaller twin corresponding to the placenta affected by MFD showed intrauterine growth restriction, with a weight below the 3rd percentile according to gestational age.

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Background: Maternal floor infarction/massive perivillous fibrin deposition (MFI/MFD), chronic histiocytic intervillositis (CHIV) and villitis of unknown etiology (VUE) are lesions of the placenta which are characterized morphologically. The cause is thought to be pathological immunotolerance/rejection reaction at the fetomaternal interface. The risk of recurrence is elevated and the lesions can lead to severe pediatric diseases.

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Objective: To characterize the clinical, diagnostic, and histopathologic findings in dogs with canine ocular gliovascular syndrome (COGS).

Procedures: The archives at the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) were used to identify eyes with COGS. Histopathological inclusion criteria included: a neovascular membrane extending from the optic nerve head or retina, clusters of spindle cells lacking vascularization within the vitreous, and histological signs of glaucoma.

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Contaminants, like pesticides, polychlorinated biphenyls (PCBs), dioxins and metals, are persistent and ubiquitous and are known to threaten the environment. Traditionally, scientists have considered the direct physiological risks that these contaminants pose. However, scientists have just begun to integrate ethology and toxicology to investigate the effects that contaminants have on behavior.

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Objective: To evaluate the incidence and risk factors associated with development of postoperative glaucoma in the Labrador Retriever following routine phacoemulsification.

Methods: Medical records from Labradors and a randomly selected population of non-Labradors were retrospectively evaluated. Signalment, diabetic status, cataract stage, gonioscopic findings, presence of preoperative lens-induced uveitis, development of postoperative hypertension (POH), postoperative glaucoma and postoperative visual status were recorded for each patient.

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Objective: To describe signalment, clinical presentation, treatment, recurrence rate, and outcome of canine conjunctival mast cell tumors (MCTs).

Design: Retrospective study.

Procedures: Canine cases were selected from the Comparative Ocular Pathology Laboratory of Wisconsin, Eye Path Lab of the UK, and California Eye Care for Animals.

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Following experts' consensus, waist circumference (WC) is the best anthropometric obesity index. However, different anatomic sites are used, and currently there is no universally accepted protocol for measurement of WC. In this study, we compare the associations between WC measured at different sites with total visceral adipose tissue (VAT) volume and cardiometabolic risk.

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Pericardial adipose tissue (PAT) is positively associated with fatty liver and obesity-related insulin resistance. Because PAT is a well-known marker of visceral adiposity, we investigated the impact of weight loss on PAT and its relationship with liver fat and insulin sensitivity independently of body fat distribution. Thirty overweight nondiabetic women (BMI 28.

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Objective: To establish the central corneal thickness (CCT) of normal koi fish by ultrasonic pachymetry, and its relationship to age, sex, body length and corneal diameter.

Methods: Age, sex and body length of 33 koi fish (17 male and 16 female fish) were recorded. Horizontal and vertical corneal diameters of each eye were obtained using Jameson calipers.

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Objective: To determine whether there is an association between evisceration with intraocular prosthesis placement via a dorsal scleral approach and decreased corneal sensitivity or aqueous tear production in dogs.

Design: Prospective study.

Procedure: Twenty-one dogs scheduled to undergo unilateral evisceration with intraocular prosthesis, and with a normal normotensive contralateral eye, based on slit-lamp biomicroscopy, indirect ophthalmoscopy and applanation tonometry, were included in the study.

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The objective of this retrospective study was to describe signalment, clinical presentation, surgical treatment, outcome, histopathologic, and immunohistochemical characteristics of periocular peripheral nerve sheath tumor in a series of cats. Six cats with a histologic diagnosis of peripheral nerve sheath tumor of the eyelid and/or conjunctiva were identified from 3997 feline ocular histopathologic submissions to the Comparative Ocular Pathology Laboratory of Wisconsin between 1976 and 2002. Medical records were reviewed and data were collected for signalment, eye affected, location, duration, and history of tumor recurrence.

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Objective: To compare sensitivity of the central and peripheral cornea of brachycephalic and Domestic Short-haired (DSH) cats.

Design: Prospective study.

Animals: Fifty DSH, thirteen Persian, and seven Himalayan cats.

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Objective: To describe signalment, ophthalmic abnormalities, and response to treatment in cats with glaucoma.

Design: Retrospective study.

Animals: Eighty-two cats with 93 glaucomatous eyes.

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An adult female neutered crossbred dog was referred in respiratory distress. Thoracic radiographs revealed tracheal narrowing with a soft tissue opacity dorsal to the trachea, near the thoracic inlet, and a patchy interstitial pulmonary infiltrate. The tracheal narrowing was thought to be due to a combination of intraluminal haemorrhage and mediastinal haemorrhage resulting from a coagulopathy caused by anticoagulant rodenticide intoxication.

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Anaphylactoid reactions to protamine sulfate have been attributed to its capacity for nonimmunologic mast cell degranulation and/or complement consumption. In the current study, evidence is presented for the occurrence of an immunologic anaphylactic reaction mediated by a complement-dependent IgG skin-sensitizing antibody. A retrospective study of blood component donors given protamine for heparin neutralization revealed that prior exposure to protamine is associated with increased risk of adverse reaction to the drug.

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