Effects of Combined and on Insulin and Paraoxonase 1 (PON1) Levels in Type 2 Diabetic Rats.

Background: Individual extracts of Garcinia kola and Kigelia africana have been shown to have therapeutic effects against a variety of variables linked to the development of diabetes mellitus. However, there is still a lack of information about the combined effects of these extracts on Insulin and Paraoxonase 1 (PON-1) in Streptozotocin-Nicotinamide-induced type-2 diabetic Wistar rats.

Methods: Forty-two young male rats (180-200g) were randomly divided into six groups (n = 7/group).