Publications by authors named "Blessed Kondowe"
Introduction: There were no systematic studies about hypoxia-related long noncoding RNAs (lncRNAs) signatures to predict the survival of patients with lung adenocarcinoma (LUAD). Setting up matching hypoxia-related lncRNA signatures was necessary.
Objective: This study aimed to establish hypoxia-related lncRNAs signatures and to seek new biomarkers to predict the prognosis of the patients with lung adenocarcinoma.
Objective: By establishing routine image interpretation presentation in the Radiology Department of Mzuzu Central Hospital (MCH), radiographers can conduct technical analysis and quality control of DR, CT among other medical imaging techniques used in clinical practice, which can effectively improve the overall level of radiographers.
Methods: Formulate the general principles of radiographer image interpretation for the Radiology Department: (1) Select typical cases and special cases to analyze the examination methods and image standard interpretation; (2) Select cases that individuals have done relatively satisfactory or unsatisfactory, or even failed to analyze the lessons learned; (3) Select normal cases to identify important imaging anatomy and describe imaging manifestations, so as to improve the basic knowledge level of imaging diagnosis and the ability to interpret images. Secondly, establish an imaging technology reading system under the perspective of new media, and extend it to real-time discussion of technical issues in an online chat group.
Objective: This study was aimed at investigating if the lymph node aspirated wash-out liquid thyroglobulin level and thyroid imaging reporting and data system (TI-RADS) nodule score can be the predictive factor for cervical lymph node metastasis in patients with papillary thyroid carcinoma (PTC).
Methods: The study included 251 patients with surgically confirmed PTC. All the patients underwent preoperative thyroid and cervical ultrasound examination using ACR TI-RADS classification, fine-needle aspiration biopsy (FNAB) for BRAF V600E gene detection, and thyroglobulin (Tg) detection in lymph node aspiration fluid.
Objective: To delve into the clinical and CT imaging manifestations of hydranencephaly, a rare congenital post-neurulation disorder occurring during the second trimester, characterized by the destruction of cerebral hemispheres and cranial cavity filled with cerebrospinal fluid (CSF). This research aims to enhance our understanding of hydranencephaly and establish a standard for its imaging diagnosis.
Methods: A retrospective analysis was conducted using the brain CT images and clinical data of 26 pediatric patients diagnosed with hydranencephaly.
Objective: To investigate the impact of two reconstruction techniques, Filtered Back Projection (FBP) and Clear View (CV) iterative algorithm, on the image quality of low-dose thin-slice chest CT.
Methods: A retrospective study of 42 patients undergoing low-dose chest CT at Mzuzu Central Hospital from Feb-Apr 2024 used automatic tube current modulation at 120 kV Raw data were reconstructed with FBP, 20% CV, 40% CV, 60% CV, and 80% CV, with 1 mm slice thickness and 0.625 mm spacing.
Objective: This study aimed to assess whether three-dimensional (3D) CT imaging improves the inter- and intra-observer reliability of peri-knee fracture classifications, compared to two-dimensional (2D) CT imaging.
Methods: A retrospective analysis was conducted on 23 patients with peri-knee fractures, using both 2D and 3D-CT scans. Three radiologists classified distal femur, patella, and tibial plateau fractures according to Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association (AO/OTA) and Schatzker systems.
Objective: This study aimed to investigate the impact of Clear View dual-domain iterative reconstruction (IR) technology on the quality of low-dose abdominal CT images and to determine the optimal weight ratio to optimize image quality.
Methods: We studied 40 patients (28 males, 12 females, aged 19-69) undergoing low-dose abdominal CT scans (CTDI = 5.32 ± 0.
Objective: The aim of this study is to compare the diagnostic value of two-dimensional (2D) CT and three-dimensional (3D) CT reconstruction techniques in detecting maxillofacial fractures in patients at Mzuzu Central Hospital (MCH).
Methods: 67 maxillofacial trauma patients admitted to Mzuzu Central Hospital from Jan to Sep 2024 underwent multi-slice spiral CT (MSCT) scanning. Images were post-processed using 2D and 3D reconstruction techniques.
Objective: To evaluate low-dose Computed Tomography (LDCT) chest vs. routine CT chest for image quality and diagnosis in suspected lung lesions, aiming to optimize LDCT protocol.
Methods: We retrospectively analyzed 85 patients with suspected lung lesions who underwent non-contrast enhanced (NCE) CT chest at Mzuzu Central Hospital from July 2023 to April 2024.