Effectiveness of a social cognition remediation intervention for patients with schizophrenia: a randomized-controlled study.

This randomized-controlled study evaluates the effectiveness of a newly developed social cognition rehabilitation intervention, the modified Social Cognition Individualized Activity Lab (mSoCIAL), in improving social cognition and clinical and functional outcomes of persons with schizophrenia recruited in two Italian sites: University of Campania "Luigi Vanvitelli" in Naples and ASST Fatebenefratelli-Sacco in Milan. mSoCIAL consists of a social cognitive training module focusing on different domains of social cognition and of a narrative enhancement module. We assessed changes in social cognition, clinical characteristics and functional variables in patients with schizophrenia who participated in 10 weekly sessions of mSoCIAL or received treatment as usual (TAU).

CALiSol-23: Experimental electrolyte conductivity data for various Li-salts and solvent combinations.

Ion transport in non-aqueous electrolytes is crucial for high performance lithium-ion battery (LIB) development. The design of superior electrolytes requires extensive experimentation across the compositional space. To support data driven accelerated electrolyte discovery efforts, we curated and analyzed a large dataset covering a wide range of experimentally recorded ionic conductivities for various combinations of lithium salts, solvents, concentrations, and temperatures.

The CPS Workers' Child Removal Decision in Cases of Domestic and Witnessed Violence.

This study aimed to explore maternal and paternal risks and protective factors that may influence the Child Protection Service (CPS) workers' child removal decision in case of domestic and witnessed violence. In all, 218 case reports of Italian CPSs were retrospectively analyzed through the Protocol of Risk and Protective Factors. The sample was then split up into two groups on the basis of the CPS professionals' placement decision after the investigation (child removal decision versus parents support and monitoring intervention).

New Challenges for Biobanks: Accreditation to the New ISO 20387:2018 Standard Specific for Biobanks.

Background: The emergence of "multi-omics" and "multi-parametric" types of analysis based on a high number of biospecimens enforces the use of a great number of high-quality (BMaD). To meet the demands of biomedical research, several Biological Resource Centers (BRCs) or Biobanks world-wide have implemented a specific Quality Management System (QMS) certified ISO 9001:2015 or accredited by CAP ISO 20387:2018. For the first time, ISO, with the support of several Biobanking experts, issued the ISO 20387:2018 which is the first ISO norm specific for Biobanks.

Parenting and the Serotonin Transporter Gene (5HTTLPR), Is There an Association? A Systematic Review of the Literature.

The current systematic review examines whether there is an association between the genetic 5-HTTPLR polymorphism and parenting, and the mechanisms by which this association operates. The literature was searched in various databases such as PubMed, Scopus, and ScienceDirect. In line with our inclusion criteria, nine articles were eligible out of 22.

Influence of 5-HTTLPR polymorphism on postpartum depressive and posttraumatic symptoms.

Introduction: Postpartum depression (PPD) is a multifactor disorder caused by psychological, social, and also biological factors. 5-HTTLPR polymorphism in the promoter region of serotonin transporter gene seems to influence PPD onset. In this study, we examined the effect of 5-HTTLPR polymorphism on prenatal and postnatal symptoms of depression and posttraumatic stress in women.

Human sample authentication in biomedical research: comparison of two platforms.

Samples used in biomedical research are often collected over years, in some cases from subjects that may have died and thus cannot be retrieved in any way. The value of these samples is priceless. Sample misidentification or mix-up are unfortunately common problems in biomedical research and can eventually result in the publication of incorrect data.

The Application of the Tissue Microarray (TMA) Technology to Analyze Cerebral Organoids.

"Multi-Omics" technologies have contributed greatly to the understanding of various diseases by enabling researchers to accurately and rapidly investigate the molecular circuitry that connects cellular systems. The tissue-engineered, three-dimensional (3D), in vitro disease model "organoid" integrates the "omics" results in a model system, elucidating the complex links between genotype and phenotype. These 3D structures have been used to model cancer, infectious disease, toxicity, and neurological disorders.

Evaluation of Benefit and Cost Utility of Immediate Postanesthesia Care Unit Radiographs to Predict Airway Compromise After Anterior Cervical Discectomy and Fusion.

Study Design: Retrospective review.

Objective: Anterior cervical discectomy and fusion (ACDF) is a commonly performed procedure that may be complicated by airway compromise postoperatively. This life-threatening complication may necessitate reintubation and reoperation.

Difficulties in emotion regulation in child abuse potential: Gender differences in parents.

Background: The Social Information Processing model (SIP; Milner, 1993, 2000, 2003) suggests that emotion dysregulation can be a moderating factor in Child Abuse Potential (CAP), influencing the processes of perception, interpretation and attribution of child's behavior.

Objective: This study aimed to evaluate comprehensively emotion dysregulation in CAP and to examine gender differences between fathers and mother at risk.

Participants And Setting: Participants were 186 mothers and 110 fathers of Italian pupils, aged 6-14 years (M = 9.

Children's Cognitive and Emotional Processes in Adult Versus Child-Related Inter-Parental Conflicts.

In the literature, little attention has been paid to the specific impact of child-related versus adult-related inter-parental conflicts on children's intrapersonal processes and adjustment. Aimed to advance knowledge on this topic, the cross-sectional study explores: 1) the predictive effects of the two forms of inter-parental conflicts on: a) children's internalizing/externalizing behaviors and b) children's cognitive appraisals, emotional distress, and triangulation; 2) the mediating role of children's cognitive appraisals, emotional distress, and triangulation, in the association between adult-related vs child-related conflict and children's adjustment. Seventy-five school-aged children and their parents completed measures of inter-parental conflict, cognitive, emotional and behavioral processes and child adjustment.

Video games use in childhood and adolescence: Social phobia and differential susceptibility to media effects.

Literature established a correlation between heavy exposure with video games (VGs) and withdrawal, loneliness, worse social skills, and social phobia. The present study hypothesizes that children with social phobia are more vulnerable to higher exposure in video gaming. Moreover, it hypothesizes that children with social phobia and higher exposure with VGs will be more at risk of developing negative outcomes such as externalizing problems.

Bullying immigrant versus non-immigrant peers: Moral disengagement and participant roles.

This study examined (1) whether self-justifying bullying (i.e., moral disengagement) differs in hypothetical bullying situations of a newcomer peer depending on his or her immigrant status; and (2) whether the respondent's immigration status, age, gender, real life bullying participant role (as bully, assistant, reinforcer, defender, victim or outsider) and moral disengagement proneness moderate the differences in moral disengagement between non-immigrant vs.

Positive Effects of Videogame Use on Visuospatial Competencies: The Impact of Visualization Style in Preadolescents and Adolescents.

Use of videogames (VGs) is almost ubiquitous in preadolescents' and adolescents' everyday life. One of the most intriguing research topics about positive effects of VG use is about the domain of visuospatial competencies. Previous research show that training with videogames enables children and adolescents to improve their scores in visuospatial tests (such as mental rotation of shapes and cubes), and that such training could overcome gender differences in these domains.

SEL1L plays a major role in human malignant gliomas.

Suppressor of Lin-12-like (C. elegans) (SEL1L) participates in the endoplasmic reticulum-associated protein degradation pathway, malignant transformation and stem cell biology. We explored the role of SEL1L in 110 adult gliomas, of different molecular subtype and grade, in relation to cell proliferation, stemness, glioma-associated microglia/macrophages (GAMs), prognostic markers and clinical outcome.

Investigating linguistic coherence relations in child sexual abuse: A comparison of PTSD and non-PTSD children.

Background: Language is the most common way to communicate internal states and emotions into a narrative form. Studies on the use of language provide a useful understanding of how people process an event and interpret it.

Objective: The aim of this study was to investigate the effects of PTSD on the narrative coherence of children's reports of sexual abuse.

Childbirth Related Post-traumatic Stress Symptoms and Maternal Sleep Difficulties: Associations With Parenting Stress.

In the literature, increasing evidence is showing the importance of sleep difficulties in the development or maintenance of posttraumatic stress (PTS) symptoms as well as the association between childbirth-related PTS symptoms and early maternal emotions and perceptions of their children. However, little is known regarding the effects of maternal sleep difficulties on parenting or about the mediational role of childbirth-related PTS symptoms in this association. The present study (pregnancy: T0; 1 month postpartum: T1; 3 months postpartum: T2) had two aims.

Correction: SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.

[This corrects the article DOI: 10.18632/oncotarget.3611.

Parents' perception of child behavior, parenting stress, and child abuse potential: Individual and partner influences.

Based on the Social Information Processing model of parenting risk for child abuse, the present study examined the associations between mothers' and fathers' perception of child behavior and child abuse potential, as well as whether parenting stress mediates the association between these constructs. Two hundred and fifty-nine mother-father couples raising preschool children answered the Child Behavior Checklist (CBCL), the Parenting Stress Index (PSI), and the Child Abuse Potential Inventory (CAPI). The results of dyadic path analysis showed that perception of child behavior was related to heightened parenting stress and abuse potential in both mothers and fathers.

Trehalose to cryopreserve human pluripotent stem cells.

The successful exploitation of human pluripotent stem cells (hPSCs) for research, translational or commercial reasons requires the implementation of a simple and efficient cryopreservation method. Cryopreservation is usually performed with dimethylsulphoxide (DMSO), in addition to animal proteins. However, even at sub-toxic levels, DMSO diminishes the pluripotency capacity of hPSCs and affects their epigenetic system by acting on the three DNA methyltransferases (Dnmts) and histone modification enzymes.

The Centrality of Events Scale for Italian Adolescents: Integrating Traumatic Experience Into One's Identity and Its Relation to Posttraumatic Stress Disorder Symptomatology.

Adolescents could develop areas of vulnerability, especially if they have had to deal with highly stressful and traumatic life events. Stressful experiences can work as traumatic memories that become central to one's life and core topics for one's identity and for the attribution of meaning to life experience. The present work evaluates (a) the internal structures of the 20-item Centrality of Event Scale in the Italian context and (b) the impact of stressful and traumatic experience during adolescence.

Childbirth Narratives of Women With Posttraumatic Stress Symptoms in the Postpartum Period.

Objective: To examine cognitive, emotional, and perceptual differences in the childbirth narratives of women with high levels of posttraumatic stress symptoms (PTSS) compared with women with low levels of PTSS in the postpartum period.

Design: A cross-sectional design. Participants were retrospectively assigned to the high or low PTSS group on the basis of their scores on the Perinatal Posttraumatic Stress Disorder Questionnaire (PPQ) administered at 1 week and 3 months after childbirth.

Generation of Human-Induced Pluripotent Stem Cells from Wolfram Syndrome Type 2 Patients Bearing the c.103 + 1G>A CISD2 Mutation for Disease Modeling.

Wolfram syndrome (WFS) is a rare autosomal premature aging syndrome that shows signs of diabetes mellitus, optic atrophy, and deafness in addition to central nervous system and endocrine complications. The frequent form of WFS type 1 (WFS1) harbors causative mutations in the WFS1 gene, whereas the rare form or WFS type 2 (WFS2) involves CISD2. Mutations in these two genes are recognized by a subset of variable clinical symptoms and a set of overlapping features.

Sel1l knockdown negatively influences zebrafish embryos endothelium.

SEL1L (suppressor/enhancer of Lin-12-like) is a highly conserved gene associated with the endoplasmic reticulum-associated degradation (ERAD) pathway and involved in mediating the balance between stem cells self-renewal and differentiation of neural progenitors. It has been recently shown that SEL1L KO mice are embryonic lethal and display altered organogenesis. To better characterize the function of SEL1L in the early stages of embryonic development, we turned to the zebrafish model (Danio rerio).

Narrative fragmentation in child sexual abuse: The role of age and post-traumatic stress disorder.

The present study aimed to assess the effects of age and PTSD on the narrative fragmentation in memories for child sexual abuse. Lexical complexity, cohesion and coherence were analyzed within a group of 86 allegations of children (M=10years; SD=3.7; range: 4-17) who were victims of sexual abuse.