Publications by authors named "Blanka Zlatohlavkova"
Article Synopsis
- This study evaluated the impact of intravenous paracetamol on postoperative pain management in extremely low birth weight (ELBW) neonates undergoing major surgery.
- The research involved 20 neonates and compared pain intensity, opioid usage, and safety outcomes between those receiving paracetamol as rescue medication and those who did not.
- Results indicated that while opioid consumption was similar in both groups, the absence of paracetamol was linked to oversedation and more instances of severe hypotension, highlighting potential benefits of paracetamol in neonatal pain management.
Article Synopsis
- The study investigates the impact of SARS-CoV-2 infection during pregnancy, focusing on maternal and fetal health in high-risk versus low-risk pregnancies.
- Conducted across 76 centers worldwide, the research looked at data from 887 infected singleton pregnancies, assessing outcomes like severe maternal morbidity and perinatal complications.
- Results indicate that high-risk pregnancies have a significantly higher likelihood of adverse maternal outcomes and hospital admissions compared to low-risk pregnancies.
Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens.
View Article and Find Full Text PDFBackground: There is no strict correlation between early bronchopulmonary dysplasia and long-term respiratory disease. Early inhaled corticosteroids seem to reduce the incidence of bronchopulmonary dysplasia, but the long-term outcome remains unknown.
Research Question: The aim of this study was to evaluate the effect of early inhaled corticosteroids on chronic respiratory morbidity.
Post-natal growth of 157 children born as extremely premature neonates.
J Paediatr Child Health
March 2011
Aim: With increasing survival rate of extremely premature neonates, their long-term outcomes including growth and risk factors for later disorders need to be considered. We prospectively evaluated anthropometric parameters in children born as extremely premature neonates.
Methods: Anthropometric parameters were measured at the ages of 2 and 5 years in 72 extremely premature children born between the 22nd and 25 + 6th weeks of gestation (group I) and 85 children born between the 26th and 27 + 6th weeks of gestation (group II).
Background: IGF-I gene polymorphisms might alter IGF-I level resulting in decreased foetal and postnatal growth and increased risk for diabetes mellitus type 2 and cardiovascular diseases in adulthood.
Objectives: We analyzed the association between Cytosine-Adenosine (CA)10-24 repeats polymorphism in promoter region of the IGF-I gene and early growth in infants with birth weight appropriate for gestational age (AGA) and small for gestational age (SGA).
Design And Methods: All neonates were born at term, 196 of them were AGA and 26 SGA.
Objective: To determine whether early surfactant administration is superior to selective delayed treatment in terms of improving survival and/or reducing chronic lung disease in extremely premature neonates with respiratory distress syndrome (RDS) treated by high-frequency oscillatory ventilation (HFOV).
Design: Prospective randomized clinical trial.
Setting: Tertiary neonatal intensive care unit (NICU) in the Perinatology Center of Prague.