Pregnancy and delivery in Leyden-Möbius muscular dystrophy. Case Report.

Leyden-Möbius muscular dystrophy is an autosomal recessive hereditary disease of unknown aetiology; it is a congenital disorder of protein metabolism primarily affecting proximal muscle groups leading to progressive muscular dystrophy. It later spreads to the muscles of the pelvic floor and lower extremities. The estimated incidence is 1:200,000.

Uterine torsion in pregnancy. Case Report.

This paper describes a case of uterine torsion not only around the long, but also the horizontal axis, diagnosed post-operatively. The patient was 28-years-old, II/I in the 34th week of her gravidity. She was admitted due to amniotic fluid leak.

Does asymptomatic carriage of FV Leiden and FII prothrombin mutations in heterozygous configuration pose an increased risk of thrombembolic complications in the course of pregnancy, labor and puerperium?

Objective: To evaluate the course of pregnancy and puerperium in asymptomatic carriers of FV Leiden and FII prothrombin mutation in heterozygous configuration in terms of risk of thrombembolic disease (TED) and late pregnancy complications. To evaluate whether global prophylactic LMWH administration during pregnancy benefits these women.

Methods: We monitored the incidence of thrombembolic events and severe late pregnancy complications in 473 asymptomatic carriers of FV Leiden and FII prothrombin mutation in heterozygous configuration.

Delayed delivery of a twin - a hazard or an acceptable method? Prospective study.

Objective: To examine the possibility of postponement of the delivery of fetus B after preterm delivery or late abortion of fetus A in multiple pregnancy.

Methods: Between January 2000 and September 2010, we tried to delay delivery of the second twin in 18 cases. Group A includes women that experienced a preterm premature rupture of the membranes in fetus A (PPROM), group B includes women who presented with regular uterine activity and the vaginal finding indicated unavoidable late miscarriage or preterm delivery.

Prospective randomised comparative study of the effect of buprenorphine, methadone and heroin on the course of pregnancy, birthweight of newborns, early postpartum adaptation and course of the neonatal abstinence syndrome (NAS) in women followed up in the outpatient department.

Objective: The aim of the study was to evaluate the effect of substitution therapy in heroin addicted pregnant women on the course of pregnancy, perinatal outcomes and course of the neonatal abstinence syndrome.

Design Of The Study: A five-year randomised prospective comparative study

Methods: The study was carried out in the period of 2002-2007. The group of patients included 147 i.