Publications by authors named "Blandine Vacquier"

Article Synopsis
  • The study investigates the increasing exposure of healthcare workers to ionizing radiation (IR) and evaluates their compliance with radiation protection (RP) policies based on their perceived risk and occupational exposure.
  • It involves healthcare workers from a French hospital, analyzing dosimetric records and responses to an online questionnaire regarding their IR exposure, risk perception, and RP knowledge.
  • Results indicate that feeling exposed to IR significantly correlates with adherence to dosimeter use and RP practices, while non-compliance is often due to inadequate RP devices, highlighting the need for improved training and awareness among workers about their exposure risks.
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Objectives: Health workers exposed to ionizing radiation account for  + 50% of workers exposed to man-made radiation in France. Over the last decade, the use of radiation in medicine has increased due to the introduction of new practices. The EXposition des Professionnels de santE aux RayonnemenTs ioniSants study aims to evaluate and characterize the trends in radiation exposure of health workers in France between 2009 and 2019.

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Article Synopsis
  • - Incidence rates of hematological malignancies have been rising over the past 40 years alongside increased usage of agricultural pesticides, yet research on the link between pesticide exposure and these cancers in the general population remains limited.
  • - A systematic review was conducted analyzing 23 studies, including various types of research designs, which found positive associations between certain pesticides and the risk of hematological malignancies, particularly in studies focused on children.
  • - Despite the suggested connection between pesticide exposure and increased cancer risk, the literature shows significant variability in study relevance and exposure assessment methods, indicating a need for more rigorous future research.
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Although medical ionizing radiation (IR) has clear clinical benefits, it is an established carcinogen. Our study estimates the number of new cancer cases in France in 2015 attributable to IR exposure from medical procedures. Exposures from external (X-rays, CT scans, interventional radiology) and internal (nuclear medicine) sources were considered.

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Radon is the second leading cause of lung cancer after smoking. Since the previous quantitative risk assessment of indoor radon conducted in France, input data have changed such as, estimates of indoor radon concentrations, lung cancer rates and the prevalence of tobacco consumption. The aim of this work was to update the risk assessment of lung cancer mortality attributable to indoor radon in France using recent risk models and data, improving the consideration of smoking, and providing results at a fine geographical scale.

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Nuclear power plants (NPPs) release toxic emissions into the environment that may affect neighboring populations. This ecologic study was designed to investigate the possibility of an excess incidence of cancer in the vicinity of French NPPs by examining the incidence by municipality of 12 types of cancer in the population aged 15 years and older during the 1995-2011 period. Population exposure to pollution was estimated on the basis of distance from towns of residence to the NPP.

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The aim of this study was to assess the risk of lung cancer death associated with cumulative lung doses from exposure to α-particle emitters, including radon gas, radon short-lived progeny, and long-lived radionuclides, and to external γ rays among French uranium miners. The French "post-55" sub-cohort included 3,377 uranium miners hired from 1956, followed up through the end of 1999, and contributing to 89,405 person-years. Lung doses were calculated with the ICRP Human Respiratory Tract Model (Publication 66) for 3,271 exposed miners.

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The adverse health effects of radon on uranium miners, especially on their lungs, are well documented, but few studies have considered the effects of other radiation exposures. This study examined the mortality risks associated with exposure to radon, external γ rays and long-lived radionuclides (LLR) in the French "post-55" sub-cohort, which includes uranium miners first employed between 1956 and 1990 for whom all three types of exposure were assessed individually. Exposure-risk relationships were estimated with linear excess relative risk models and a 5-year lag time.

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Objectives: The few studies examining the risk of circulatory system diseases (CSD) associated with ionizing radiation have reported inconsistent results. Radon, a known pulmonary carcinogen, emits ionizing radiation. The aim of this study was to examine CSD mortality in a French cohort of uranium miners and evaluate the plausibility of an association with radon exposure.

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This case-control study nested in the French cohort of uranium miners provides an opportunity to take account of silicosis and smoking in the assessment of the relation between radon and lung cancer. The study includes 100 miners who died of lung cancer and 500 matched controls born within the same period of birth and of the same age at the time of death of the matching case. Data on radon exposure are obtained from individual monitoring of the miners, and data on smoking come from medical records and interviews.

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Radon is classified as a known pulmonary carcinogen in humans. A better understanding of the effects of low exposure and time-dependent factors, modifying the lung cancer risk is of continued interest. We present analyses of the exposure-risk relationship in the French cohort of uranium miners updated until 1999 and including five additional years of follow-up.

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