Publications by authors named "Blandine Prevost"
Article Synopsis
- Acute bronchiolitis is a major public health issue, leading to many infant hospitalizations, with a notable decrease during the COVID-19 pandemic raising concerns about a potential resurgence afterward.
- A study assessed bronchiolitis severity and viral agents by comparing infant hospitalizations over a 5-year span—two years before COVID, during COVID, and two years after.
- Findings showed that while hospital admissions were similar pre- and post-COVID, bronchiolitis severity increased post-pandemic, particularly among younger infants with higher rates of RSV infections, underscoring the need for effective preventive measures.
Article Synopsis
- RSV is a major cause of bronchiolitis, leading to 3 million hospitalizations each year, and nirsevimab is a monoclonal antibody aimed at preventing severe RSV cases in infants.
- A study compared infants hospitalized for RSV bronchiolitis with those visiting for unrelated reasons, assessing nirsevimab’s effectiveness in preventing hospitalizations in those under 12 months old.
- Findings showed nirsevimab reduced hospitalization rates for RSV-associated bronchiolitis by 83% and critical care needs by about 70%, indicating it is an effective treatment option for vulnerable infants.
Objectives: To identify with children, parents and physicians the objectives to be used as parameters for algorithmic decision-making systems (ADMSs) adapting treatments in childhood asthma.
Methods: We first conducted a qualitative study based on semi-structured interviews to explore the objectives that children aged 8-17 years, their parents, and their physicians seek to achieve when taking/giving/prescribing a treatment for asthma. Following the grounded theory approach, each interview was independently coded by two researchers; reconciled codes were used to assess code frequency, categories were defined, and the main objectives identified.
Tuberculosis (TB) poses a major global health threat, substantially affecting children, who contribute notably to new cases and deaths. Diagnosing TB in kids is challenging due to collection issues and the paucibacillary nature of the disease. Disseminated TB, uncommon in children in low TB incidence countries, remains a significant cause of morbidity in migrant populations.
View Article and Find Full Text PDFIntroduction: Lung biopsy is considered as the last step investigation for diagnosing lung diseases; however, its indication must be carefully balanced with its invasiveness. The present study aims to evaluate the diagnostic yield of lung biopsy in critically ill patients hospitalized in the pediatric intensive care unit (ICU).
Material And Methods: Children who underwent a lung biopsy in the ICU between 1995 and 2022 were included.
New technologies enable the creation of digital twin systems (DTS) combining continuous data collection from children's home and artificial intelligence (AI)-based recommendations to adapt their care in real time. The objective was to assess whether children and adolescents with asthma would be ready to use such DTS. A mixed-method study was conducted with 104 asthma patients aged 8 to 17 years.
View Article and Find Full Text PDFThe coronavirus disease 2019 (COVID-19) outbreak has evolved with different waves corresponding to subsequent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations. While the most severe cases have been observed in the elderly and in individuals with underlying comorbidities, severe pediatric and young adult cases have been observed, as well as post-infectious inflammatory syndromes and persistent symptoms leading to long-COVID. This manuscript describes the experience of a pediatric respiratory unit during the first year of the pandemic and reviews the corresponding literature with a special emphasis on children and young people with underlying conditions, such as immunosuppression, sickle cell disease, and cystic fibrosis.
View Article and Find Full Text PDFArticle Synopsis
- * Of the 7,485 pediatric COVID-19 cases studied, 26.6% (1,988 patients) were admitted to critical care units, with younger age, pediatric multisystem inflammatory syndrome (PIMS), respiratory issues, and underlying conditions being significant risk factors.
- * The rate of critical care admissions decreased over the pandemic waves, with a total of 32 deaths (0.4%) and a median age of 6 years among those who died, highlighting specific age groups, especially newborn
Background: In the midst of successive waves of SARS-CoV-2 variants, the B.1.1.
View Article and Find Full Text PDFBackground: Although bronchoscopy can be part of the exploration of severe asthma in children, the benefit of bronchoalveolar lavage (BAL) is unknown. The present study aimed to decipher whether systematic BAL during a flexible bronchoscopy procedure could better specify the characteristics of severe asthma and improve asthma management.
Material And Methods: The study took place in two departments of a university hospital in Paris.
Ten months after its appearance in December 2019, SARS-CoV-2 has infected more than 25 million patients worldwide. Because children were first identified as potential spreaders of the virus, schools were closed in several countries. However, it rapidly became evident that the number of hospitalized children infected by SARS-CoV-2 was dramatically lower than that of adults.
View Article and Find Full Text PDF