Depressive symptoms in pregnant women with high trait and state anxiety during pregnancy and postpartum.

Depression and anxiety are frequent during pregnancy, and epidemiological studies demonstrate high rates of co-morbidity. To evaluate the association between the trait and state anxiety and depressive symptoms in women during the perinatal period. A transversal study was conducted at the National Institute of Perinatology (INPer, Mexico City) from 2012 and 2015.

Modification of sleep architecture in an animal model of experimental cirrhosis.

Aim: To analyze the polygraphic sleep patterns during cirrhosis progression in a rat model by repeated CCl(4) administration.

Methods: Male Wistar rats received three weekly injections of CCl(4) for 11 wk, and were analyzed before and during the induction of cirrhosis. Rats were implanted with electrodes to record their sleep patterns.

Effective use of FibroTest to generate decision trees in hepatitis C.

Aim: To assess the usefulness of FibroTest to forecast scores by constructing decision trees in patients with chronic hepatitis C.

Methods: We used the C4.5 classification algorithm to construct decision trees with data from 261 patients with chronic hepatitis C without a liver biopsy.

Acetaldehyde-induced mitochondrial dysfunction sensitizes hepatocytes to oxidative damage.

Acetaldehyde (Ac), the main metabolite of ethanol oxidation, is a very reactive compound involved in alcohol-induced liver damage. In the present work, we studied the effect of Ac in mitochondria functionality. Mitochondria from Wistar rats were isolated and treated with Ac.