Publications by authors named "Blake Weis"

A 66-year-old woman reported 10 days of generalised weakness, falls and memory 'glitches'. She had developed left-sided ophthalmic herpes zoster 3 months before but was otherwise well. MR scan of brain showed acute left-sided ischaemic strokes and CT cerebral angiogram identified marked stenoses of the left anterior and middle cerebral arteries.

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Article Synopsis
  • The study investigates the challenge of differentiating cerebral radiation necrosis (RN) from tumor recurrence after radiation treatment, noting existing diagnostic difficulties with standard MRI and the lack of evidence-based guidelines.
  • A systematic review and meta-analysis were conducted on various imaging techniques, including MRI, MR Spectroscopy (MRS), and PET, analyzing data from 127 studies and 220 imaging datasets.
  • Results showed that MRS had the highest sensitivity (90.7%) and DTI had the highest specificity (90.5%), with SPECT and MRS being ranked as the most effective options for differentiating RN from tumor recurrence in comparison to standard MRI.
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